Most cases of conjunctivitis are self-limited. Treatment of bacterial conjunctivitis enhances the resolution of the infection and includes administration of proper topical antibiotics selected according to the antimicrobial susceptibility of the infecting organism. Conjunctivitis caused by anaerobes should be treated by antimicrobial agents effective against these organisms. Bacitracin is very active against Peptostreptococcus spp. but is generally inactive against B.fragilis and Fusobacterium nucleatum (9). Erythromycin shows good activity against pigmented Prevotella and Porphyromonas, microaerophilic and anaerobic streptococci, and gram-positive non-spore-forming anaerobic bacilli. Erythromycin has relatively good activity against Clostridium spp. but poor and inconsistent activity against gram-negative anaerobic bacilli. Chloramphenicol has the greatest in vitro activity against anaerobes, but should be used cautiously because it is absorbed from the conjunctivae. Anaerobic gram-positive cocci, the anaerobes most frequently recovered from inflamed conjunctivae, are susceptible to penicillins, macrolides, and chloramphenicol. Anaerobic bacteria may be relatively resistant to sulfona-mide, the older quinolones, polymixin B, and aminoglyloside preparations that are commonly applied to inflamed conjunctiva. Since anaerobes may be involved in severe cases of conjunctivitis and especially with the most serious complications of bacterial conjunctivitis, such as a penetrating corneal ulcer or orbital cellulitis, specific coverage for these organisms should be considered. In such instances, administration of parenteral antimicrobial agents should supplement the topical application of medications.

The Natural Acne Remedy

The Natural Acne Remedy

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