1. Any tissue or body fluid should be considered as potentially infectious, although in reality the main danger probably lies in accidental inoculation. However, there is nothing to suggest that routine nursing care carries a risk, therefore barrier nursing is unnecessary. Accidental transmission has occurred by contaminated instruments, and a cadaveric dural graft (Lane et al 1994), or by pituitary hormones from cadavers before the use of recombinant growth hormone (Holmes et al 1996). Martinez-Lage et al (1994) have described four patients who developed CJD from lyophilised dura mater grafts.
2. Occasionally patients may have autonomic dysfunction.
3. Rarely, there are abnormalities of liver function.
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