Conns syndrome primary aldosteronism

Excess aldosterone production may be caused by an adrenal adenoma, adrenal hyperplasia, or a carcinoma. For a differential diagnosis of the different features, see Ganguly (1998). Aldosterone is a mineralocorticoid secreted by the zona glomerulosa of the adrenal cortex. It promotes sodium reabsorption and potassium exchange, mainly in the renal tubules, but to a lesser extent in the intestine, and salivary and sweat glands.The final stage of aldosterone secretion is controlled by the renin-angiotensin system. Activation of this system occurs in response to sodium or water depletion. Primary aldosteronism should be suspected if spontaneous hypokalaemia occurs in association with untreated hypertension (Young 1997, Stewart 1999).

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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