Eisenmengers syndrome

A rare syndrome of pulmonary hypertension associated with a reversed or bidirectional cardiac shunt, occurring through a large communication between the left and right sides of the heart.The defect may be interventricular, interatrial, or aortopulmonary. The development of Eisenmenger's syndrome, from the initial left to right shunt, is usually a gradual process. Contributory factors to the pulmonary hypertension are hypoxia, high pulmonary blood flow, and high left atrial pressure. Irreversible structural changes take place in the small vessels, causing pulmonary vascular obstruction and a reduction in the size of the capillary bed.The pulmonary artery pressure is the same as, or sometimes exceeds, the systemic arterial pressure.The incidence of this syndrome is decreasing because of the more vigorous approach to diagnosis and treatment of congenital heart disease in childhood. In a long-term study of 188 patients over a median period of 31 years, noncardiac surgery with general anaesthesia carried risks of 23.5%, and pregnancy was associated with a deterioration in physical status and a maternal mortality of 27% (Daliento et al 1998).A lower mortality (10%) was quoted in a series of nonparturients, but only half involved general anaesthesia (Raines et al 1996). The mortality is also lower in children (Lyons et al 1995).

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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