H

Type B

Aortic

Dissection

Control

Figure 16.3. (a) Plasmatic levels detected by ELISA of metalloproteinase-9 from symptom onset to two months' follow-up in type B aortic dissection. No MMP-9 are measurable in the control population presenting in the emergency room with chest pain.

Figure 16.3. (Continued) (b) Micrograph showing the aortic wall (hematoxilin eosin, left upper panel, magnification x4) with immunohistochemical staining for Cox2 (central upper panel, magnification x4) and MMP-9 (right upper panel, magnification x4) from a patients affected by type A aortic dissection and operated in the subacute phase (7-10 days after symptom onset). Note the marked inflammatory infiltrate demonstrated by strong positivity to Cox2 (small black insert, magnification x20) and the presence of MMP-9 within inflammatory cells (small black insert, magnification x20) in the nj same region of the aortic wall.

Figure 16.3. (Continued) (b) Micrograph showing the aortic wall (hematoxilin eosin, left upper panel, magnification x4) with immunohistochemical staining for Cox2 (central upper panel, magnification x4) and MMP-9 (right upper panel, magnification x4) from a patients affected by type A aortic dissection and operated in the subacute phase (7-10 days after symptom onset). Note the marked inflammatory infiltrate demonstrated by strong positivity to Cox2 (small black insert, magnification x20) and the presence of MMP-9 within inflammatory cells (small black insert, magnification x20) in the nj same region of the aortic wall.

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