Other Agents

No data exist for the use of other vasodilator agents (such as angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, diuretics, or

Figure 10.1. Changes in the aortic ratio in the beta-blocker group and the control group. The aortic ratio is the ratio of the diameter of the aorta measured in a patient to the diameter expected in a subject with the same body-surface area and age. The ratio in each patient is presented here as a fitted regression line: the data points are not shown, but the length of each line indicates the length of follow-up. One patient in the control group had an exceptional aortic ratio (>3.4) at 100 months. Two patients in the beta-blocker group (arrows) did not comply with propranolol therapy. Adapted from Shores et al.1

Figure 10.1. Changes in the aortic ratio in the beta-blocker group and the control group. The aortic ratio is the ratio of the diameter of the aorta measured in a patient to the diameter expected in a subject with the same body-surface area and age. The ratio in each patient is presented here as a fitted regression line: the data points are not shown, but the length of each line indicates the length of follow-up. One patient in the control group had an exceptional aortic ratio (>3.4) at 100 months. Two patients in the beta-blocker group (arrows) did not comply with propranolol therapy. Adapted from Shores et al.1

alpha blockers) in the setting of chronic aortic disease. Logic would dictate that such agents would be of benefit for their antihypertensive effects, but only in the presence of good heart rate control with a beta blocker (preferred) or calcium blocker.

Figure 10.2. Empirical distribution functions of the rate of change in the aortic ratio, according to study group. The height of each curve at any point shows the proportion of patients with values at or below the value given on the x axis. There is little overlap between the beta-blocker treated and control groups. Adapted from Shores et al.1

Rate of Change in Aortic Ratio (per Year)

Figure 10.2. Empirical distribution functions of the rate of change in the aortic ratio, according to study group. The height of each curve at any point shows the proportion of patients with values at or below the value given on the x axis. There is little overlap between the beta-blocker treated and control groups. Adapted from Shores et al.1

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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