Clinical Presentation Of Pcnsl

Clinical presentation of CNS lymphoma may be characterized by headaches, confusion, lethargy, memory loss, hemiparesis, aphasia, and seizures. Lesions are most common in the cerebrum, basal ganglia, and brainstem.14,29 The lesions are usually large, few in number, and contrast enhanced on neuroimaging. In the pre-HAART era, most patients with PCNSL were near the late stages of AIDS, with the majority dying within 4-6 weeks of diagnosis with supportive care alone.30

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