42 patients with Behcet's disease fulfilling the ISG criteria were grouped in three groups, namely those presenting deep vein thrombosis (DVT), those with DVT + superficial vein thrombosis (SVT), and those with chronic venous insufficiency (CVI), and were assessed according to their demographic data, clinical prognosis and treatment. We also used radiological imaging techniques (Doppler US) during follow-up.
Treatment given to these patients was classified in three groups:
a) Colchicine + anticoagulants-antiaggregants b) Corticosteroids + anticoagulants-antiaggregants c) Immunosuppressives + anticoagulants-antiaggregants
Their response to treatment was summoned in three groups:
a) Full response to treatment and no activation: Clinical full remission and no recurrence b) Persistence of existing vascular involvement: Persistence and chronicity of the present clinical state c) Addition of new vascular involvements to the present one and CVI.
Their response to treatment was evaluated both clinically and radiologically. The response to treatment assessed by Doppler US was defined in three categories:
a) Full response: Total recanalisation and near to normal Doppler US
b) Partial response: Partial recanalization with collateral formation c) No response: Addition of new thromboses to the existing ones.
Doppler US was applied to 40 of 42 patients before treatment. The procedure was applied to only 22 of them after treatment due to socioeconomical incapabilities. This includes 2 patients who were not radiologically evaluated before the treatment.
The treatment was classified according to drug given, dosing of the drug, and duration of treatment. The response to treatment was assessed according to clinical criteria and the Doppler US criteria. The remission period for each drug given was defined separately. While considering the remission period, the remission periods for the patients with full clinical response and no activation were taken into account, while the remission periods for the patients with no clinical response and with clinical activation were excluded.
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