Cercopithecine herpesvirus 7 CeHV7 An

Unassigned species in the subfamily Alphaherpesvirinae. Isolated from captive patas monkeys, Cercopithecus patas, with a severe exanthematous disease. Synonyms patas monkey herpesvirus delta herpesvirus. Felsenfeld AD and Schmidt NJ (1979) J Gen Virol 42, 171 McCarthy K et al (1968) Lancet ii, 856 Cercopithecine herpesvirus 8 (CeHV-8) A species in the genus Cytomegalovirus. Causes persistent infection of rhesus monkeys, Macaca mulatta. Genome DNA is 52 G+C. Synonym rhesus monkey...

Latent hamster virus See Hamster polyomavirus

Latent infection An infection in which infectious virus is not demonstrable until activated. The classic example is that of Human herpesvirus 1 infection of the dorsal root ganglia between episodes of 'cold sores'. Only a small region of the virus genome is expressed during latency yielding 'latency-associated transcripts' (LATs), and no infectious virus can be found. The role of the LATs is unclear, as they are not essential to maintain latency. In response to certain stimuli, such as...

Baby hamster kidney cells See BHK21 cells

Bacajai virus A virus in the genus Orbivirus isolated from phlebotomine sandflies in the Amazon region of Brazil. Antigenically related to the Changuinola virus serogroup. bacilliform Description of the shape of certain virus particles which are cylindrical with two rounded ends. bacteriocinogen A plasmid DNA present in certain strains of bacteria, which specifies production of a bacteriocin. Normally the bacteriocinogen is repressed, and the cell carrying it does not produce bacteriocin. The...

Macropodid herpesvirus 1 MaHV1 An

Unassigned species in the subfamily Alphaherpesvirinae. Isolated from a culture of kidney cells of a parma wallaby, Macropus parma. The animal was one of a number with a fatal generalized disease taken from Kawan Island in Auckland Bay, New Zealand. The culture developed foci of CPE which extended rapidly. Experimental infection of Parma wallabies causes a severe generalized disease with lesions in lungs and liver. Antibodies are found in a wide range of macropods (kangaroos and wallabies) from...

Cote dlvoire Ebola virus Ciebov A

Species in the genus 'Ebola-like viruses', isolated from a woman who became ill with Ebola fever after examining a dead chimpanzee in the Tai forest, Cote d'Ivoire, in 1994. Genetically distinct from other Ebola virus isolates. Cotia body Inclusion body seen late in infection with Cotia virus. Eosinophilic when stained with hematoxylin and eosin, but appears as a reddish-purple ring with an inner pale blue area when stained with Giemsa. Morphologically different from those of Cowpox and other...

Chamois contagious ecthyma virus

Tentative species in the genus Parapoxvirus. Causes lesions similar to those produced by Goatpox virus, but the lesions are primarily around the lips and mouth, and infrequently on the udder, thighs, anus, nostrils and eyes. Antigenically different from Goatpox virus and the two do not cross-protect. An important cause of disease in sheep, and a live vaccine is used. As virus remains active in scabs for a long period the vaccine is used annually. Occurs in many parts of the world. Synonyms...

Plating efficiency See efficiency of plating

Playas virus (PLAV) A serotype of Bunyamwera virus in the genus Bunyavirus. Isolated from mosquitoes, Aedes taeniorhynchus, in Ecuador. Not known to cause disease in humans. pleconaril An antiviral compound that inhibits picornavirus replication and is active in mice by oral administration. Binds to the hydrophobic pocket of the virion capsid. Clinical trials against enterovirus and rhinovirus infections are underway. pleuronectid herpesvirus (PiHV-1) An unas-signed virus in the family...

G

GA391 virus A strain of Lassa virus in the G protein Name used for the major glyco-protein of a number of viruses, especially negative-strand viruses. Gabek Forest virus (GFV) A tentative species in the genus Phlebovirus, belonging to the sandfly fever virus group. Isolated from the spiny mouse, Acomys cahirinus (albigena). The vector species has not yet been determined. Gadget's Gully virus (GGYV) An unas-signed tick-borne species in the genus Flavivirus. Isolated from ticks, Ixodes...

Inclusion body hepatitis IBH of chickens

A disease caused by several different species in the genus Aviadenovirus. Causes a common and often fatal disease of chickens. At least 10 serotypes of Fowl adenovirus have been associated with natural outbreaks. There are liver lesions, intramuscular hemorrhages and aplastic anemia. Yolk-sac inoculation of chick embryos causes death. Plaques are produced on the CAM. Birds with antibodies and eggs from such birds are resistant to infection. Fadley AM and Winterfield RW (1975) Am J Vet Res 36,...

Threeday stiffsickness virus Synonym for

Greek thylax sac) A name suggested for the RNA tumor viruses by Professor Gilbert Highet, Head of Department of Greek and Latin, Columbia University. Not adopted. Dalton AJ et al (1966) J Natl Cancer Inst 37, 395 thymidine kinase (TK) An enzyme which is induced in cells infected with some DNA viruses and which catalyzes the phosphorylation of thymidine to thymidylic acid. In papovavirus-infected cells the induced enzyme is cellular in origin, but the thymidine...

AKR mink cell focusinducing virus A

Possible subspecies in the genus Gammaretrovirus. A helper independent virus isolated from AKR thymoma cells. Probably a recombinant between ecotropic AKR mouse leukemia virus and a xenotropic virus. Hartley JW et al (1977) Proc Natl Acad Sci 74, 789 AKT The oncogene specified by AKT8 virus. The human cellular homologs, known as c-AKT1 and c-AKT2, encode protein kinase C-related serine threonine kinases. AKT8 virus A probable species in the genus Gammaretrovirus. An acute transforming strain of...

Marmoset herpesvirus Synonym for

Marmosetpox virus (MPV) An unassigned virus in the family Poxviridae. Virion morphology like Yatapox virus. Marrakai virus (MARV) A serotype of Palyam virus in the genus Orbivirus. Isolated from the mosquitoes Culicoides schultzei and C. perigrinus in Northern Territory, Australia. Marshall-Regnery myxoma virus A strain of Myxoma virus in the genus Leporipoxvirus. Isolated from the California brush rabbit. marsupial papillomavirus Synonym for quokka poxvirus. marsupial poxvirus See quokka...

IgM See immunoglobulin

Iguana virus Synonym for iguanid her-pesvirus 1. iguanid herpesvirus 1 (IgHV-1) A possible species in the family Herpesviridae. Isolated from a spontaneously degenerating cell culture of tissue from a green iguana, Iguana iguana. On injection into iguanas it caused no consistent disease pattern observable on necropsy, but 7 of 12 animals injected died. Has narrow host range. Replicates in iguana cell cultures with CPE at certain temperatures. Synonyms iguana virus green iguana herpesvirus....

Hepatitis GB viruses See GB viruses

Hepatitis infectiosa canis virus Synonym for Canine adenovirus. hepatitis non-A non-B virus In the mid-1970s, when diagnostic tests were established for Hepatitis A and Hepatitis B viruses, it became clear that much transfusion-related hepatitis was not caused by either virus. The term 'non-A non-B' was used together with a diagnosis of exclusion to describe the agent(s) responsible for this disease. See Hepatitis C, E, F, G and GB viruses. hepato-encephalomyelitis virus Prototype strain of...

JHM virus See JHM strain of mouse hepatitis virus

Jijoye cells (CCL 87) A cell line derived from ascitic fluid of an African black boy with Burkitt's lymphoma of the liver. The cells contain an unidentified herpes-like virus. JKT-6423 JKT-6969 JKT-7041 JKT-7075 viruses Indonesian isolates of probable members of the genus Coltivirus, family Reoviridae. Joa virus (JOAV) A serotype of Frijoles virus in the genus Phlebovirus. Not reported to cause disease in humans. Joest-Degen bodies Acidophilic intranuclear inclusion bodies found in the brain...

Ecthyma contagiosum of sheep virus

Ectromelia virus (ECTV) A species in the genus Orthopoxvirus which is a natural pathogen of mice. Serologically related to Vaccinia virus. A latent infection, endemic in many mouse stocks, activated by stress. Injection i.p. into mice causes death from hepatitis. Injection into the skin of rabbits, guinea pigs and cotton rats produces local lesions which can be prevented by immunization with Vaccinia virus. Replicates slowly on the CAM, with small, white, irregularly shaped pocks appearing in...

Lymphocystis disease virus 2 LCDV2 A

Tentative species in the genus Lymphocystivirus, varying in size from 130 to 300nm. Lymphocystis is a common, chronic, but rarely fatal disease affecting fish of several of the higher orders. The infection is found worldwide in numerous species of fish, both marine and freshwater. Tumor-like masses appear on the skin and fins, persist for long periods, but ultimately regress. They are caused by massive increases (100000-fold) in the size of infected cells, which contain large cytoplasmic...

Infectious bovine rhinotracheitis virus

Infectious bronchitis virus (IBV) The type species of the genus Coronavirus. The cause of a common, contagious, acute respiratory disease of chicks. Neutralization tests using chick embryos indicate multiple variant antigenic types. All strains show some antigenic relationships but are unrelated to other coronaviruses. Beaudette strain (IBV-42) is serologically similar to Massachusetts strain, although on egg passage it has become lethal for chick embryos but has lost infectivity for older...

Sphenicid herpesvirus 1 SpHV1 An

Unassigned virus in the family Herpesviridae. Isolated from a black-footed penguin, Spheniscus dermersus. Synonym black-footed penguin her-pesvirus. Kincaid AL (1988) J Wildl Dis 24,173 spider monkey herpesvirus Synonym for Ateline herpesvirus 1. spike A projection from the surface of a virus particle, usually associated with binding of the particle to the cell surface. See peplomers. spiking disease Turkey enteritis caused by Turkey coronavirus. spleen focus-forming virus A strain of Murine...

Epidermodysplasia verruciformis EV

Widespread and persistent dissemination of flat warts (verruca plana), sometimes for decades, which can progress to malignancy. Often associated with HPV types 5 and 8. Found particularly in immuno-suppressed persons, e.g. AIDS patients. Synonym Lewandowsky-Lutz disease. episomes Plasmids which can be integrated into the cell genome, where they behave as part of a chromosome. Phage lambda is an example. May behave as an episome in one cell and a plasmid (replicating independently of the...

Perch hyperplasia virus PHV A tentative

Species in the genus Epsilonretrovirus. Sequence analysis of the pol gene showed a phylogenetic similarity to the type species, Walleye dermal sarcoma virus. perch iridovirus An iridovirus was isolated from pike-perch, Stizostedion lucioperca, fingerlings with no sign of disease. Tapiovaara H et al (1998) Dis Aquat Org 32, 185 perch rhabdovirus An unassigned member of the genus Lyssavirus, family Rhabdoviridae. Isolated from yearling perch, Perca fluviatilis, in France. Causes a CNS disorder...

Pinocytosis See viropexis

Piratuba virus A possible species in the genus Orbivirus, isolated from mosquitoes in the Amazon region of Brazil. Antigenically related to Changuinola virus. Not associated with disease in humans. Pirital virus (PIRV) A species in the genus Arenavirus isolated in Venezuela. Natural rodent host is the cane rat, Sigmodon alstoni. Not known to cause human disease. Genetically related to Tacaribe complex viruses. Pirodavir An antiviral compound that inhibits picornavirus replication by binding to...

Cercopithecine herpesvirus 12 CeHV12 A

Species in the genus Lymphocryptovirus. Isolated from cell lines established from splenic lymphocytes of a baboon, Papio hamadryas, by co-cultivation with X-irradiated marmoset or baboon lym-phoblastoid cell cultures. The baboon had been injected with blood from another baboon which had been injected with human blood and had a lymphoma. The cell lines have B lymphocyte characteristics and carry a virus related to, but not identical with, Epstein-Barr virus as demonstrated by cross-reactivity of...

Feline cellassociated herpesvirus FCAHV

See also felid herpesvirus 2. Feline coronavirus (FcoV) A species in the genus Coronavirus. Antigenically related to porcine Transmissible gastroenteritis virus but infection with Transmissible gastroenteritis virus does not give immunity to infectious peritonitis. Cats of any age, leopards and other large cats are susceptible. Causes a gradual loss of appetite, wasting and abdominal distension due to fibrinous peritonitis. Fatal in a few weeks. There is often...

Clone 15c4 cells See Chang conjunctiva cells

Cloned library A collection of cloned DNA sequences representative of the genome under study. cloning 1. Molecular cloning is the production of many identical copies of a gene from a single gene inserted into a cloning vector. 2. Cell cloning is the production of genetically identical cells from a single cell. 3. Virus cloning from a mixed population can be achieved by repeatedly picking a single plaque and so selecting a single replicating species. cloning vector Any DNA molecule capable of...

Ross goose hepatitis B virus Rghbv An

Unassigned virus in the family Hepadnaviridae. Ross River virus (RRV) A species in the genus Alphavirus. Isolated from birds and mosquitoes in Fiji, and Queensland and New South Wales, Australia. Causes a febrile illness and rash with arthralgia in humans. The vectors are the mosquitoes, Aedes vigilax and Culex annulirostris. Antibodies are present in horses, cattle, sheep, dogs, rats, bats and kangaroos in northern and eastern Australia, New Guinea and northern Solomon Islands. Aaskov JG and...

DsRNA adenosine deaminase activity See DRADA

D-type virus particles A term used originally to describe the 30nm non-enveloped particles seen in large numbers in cell nuclei from poly-omavirus-infected mice and hamsters. They proved to be polyomavirus particles and the term passed out of use. However, in their proposed classification of Retroviridae Dalton et al suggested a genus oncornavirus D, with Mason-Pfizer monkey virus as the type species. This has resulted in the Mason-Pfizer virus and morphologically similar viruses being...

Japanese hemagglutinating virus

Jari virus JARIV A serotype of Changuinola virus in the genus Orbivirus. Isolated from the sloth, Choloepus didacty-lus, in Para, Brazil. Jatobal virus A possible species in the genus Bunyavirus, isolated from a carnivore Nasua nasua in the Amazon region of Brazil. Not associated with disease in humans. It is a reassortant virus containing one segment S derived from Oropouche virus. Jatuarana virus A possible species in the genus Orbivirus, isolated from phle-botomine sandflies in the Amazon...

Walleye herpesvirus See percid herpesvirus

Walrus calicivirus WCV An unassigned virus in the family Caliciviridae, isolated from the feces of the walrus, Odobenus rosmarus, collected off sea ice in the Chukchi Sea. Smith AW and Boyt PM 1990 J Zoo Wildl Med 21, 3 Smith AW et al 1983 J Wildl Dis 19, 86 Wanowrie virus WANV An unassigned virus in the family Bunyaviridae. Isolated from the tick, Hyalomma marginatum isaaci, and the mosquito, Culex fatigans, in India, Sri Lanka and Egypt. Has been isolated from the brain of a patient with...

Duck hepatitis virus 1 and 3 DHV1 and

-3 Unassigned viruses in the family Picornaviridae, often referred to as 'enteroviruses' there are two serotypes, 1 and 3. Cause a widespread infection of ducks with disease in ducklings. There is hemorrhagic necrosis of the liver and high mortality. Older birds are immune. Virus is present in the excreta. Birds hatched from the eggs of immune birds resist infection. Virus replicates in hens' eggs, killing the embryo, but becomes attenuated on passage and may be used as a vaccine for ducklings....

Sapporo virusSapporo HuSLVSV1982

JP A strain of Sapporo virus in the genus 'Sapporo-like viruses'. Saquinavir A licensed antiviral drug, an inhibitor of the HIV protease, also known as Ro31-8959. Extremely active inhibitor of HIV replication in cell culture. A pep-tide-based transition state mimetic of the protein cleavage site. Synonym Invirase. Roberts NA et al 1990 Science 248, 358 Srinivas RV and Fridlund A 1999 In Encyclopedia of Virology, Second edition, edited by A Granoff and RG Webster. London Academic Press, p. 778...

Channel catfish herpesvirus CCHV

Channel catfish reovirus CRV A strain of Aquareovirus D in the genus Aquareovirus, isolated from catfish, Ictalurus punctatus, but not associated with disease. Chinchar VG et al 1996 Dis Aquat Org 33, 77 Hedrick RP et al 1984 J Gen Virol 65, 152 Chargaff's rule In double-stranded DNA molecules, the proportion of adenine equals that of thymine, and the proportion of guanine equals that of cytosine. This results from the pairing of the bases. Charleville virus CHVV An unassigned vertebrate...

Spleen necrosis virus A strain of

Spliceosome A multicomponent ribonucle-oprotein complex that carries out the splicing of RNA. splice sites The sites at which the intron is excised. The 5' splice site is adjacent to the GU end of the donor junction. The 3' splice site is adjacent to the AG end of the acceptor junction. splicing Ligation of non-contiguous cleaved portions of an RNA molecule to remove introns from precursor RNA transcripts and produce functional mRNA. Originally discovered from work on adenovirus mRNA synthesis....

Sororoca virus Sorv A strain of

Wyeomyia virus in the genus Bunyavirus, belonging to the Bunyamwera serogroup. Isolated from mosquitoes of Sabethini sp in Para, Brazil. Not reported to cause disease in humans. Sotkamo virus A strain of Puumula virus isolated from the rodents, Clethrionomys glareolus and Clethrionomys rufocanus, in Finland. Vapahlati O et al 1992 J Gen Virol 73, 829 Southampton virus SHV A serotype of Norwalk virus, in the genus 'Norwalk-like viruses'. Isolated from a family outbreak of gastroenteritis in...

Fetal rhesus kidney virus Synonym for

A-fetoprotein AFP A protein present in the serum of vertebrate embryos. Presence in the amniotic fluid is diagnostic for spina bifida in the human fetus. Serum levels of AFP are normally less than 20 ng ml, but may rise above 1000 ng ml when hepatocellular carcinoma frequently associated with Hepatitis B or C virus infection is present. Feulgen stain One of the few staining methods specific for DNA. FHM cells CCL 42 A heteroploid cell line derived from tissue posterior to the anus, exclusive of...

Simian type D virus SRV1 A strain of

Mason-Pfizer monkey virus in the genus Betaretrovirus. There are five serotypes based on neutralization by antisera. Causes immunosuppression SAIDS-D in macaque monkeys and originally called simian AIDS D-type SAIDS-D virus. Virions have a type D morphology and lack prominent spikes. The genome is typical of a retrovirus, with the structure 5' -gag-pro-pol-env-3' and no oncogenes. Reverse transcriptase has a preference for magnesium rather than manganese and is primed by tRNALys. Virions induce...

Murine gammaherpesvirus MHV68 See Murid herpesvirus

Murine hepatitis virus MHV A species in the genus Coronavirus. Serologically related to Rat coronavirus and sialo-dacryoadenitis virus of rats. Often a silent infection of laboratory mice which may be activated by passage of other viruses such as leukemia virus, or by cortisone, urethane or enterotoxin from Gramnegative bacteria, or by thymectomy. Injection of virus into mice infected with the parasite Eperythrozoon coccoides usually produces fatal hepatitis but in its absence there is often no...

Equine morbillivirus EMV See Hendra virus

Equine papillomavirus EqPV A possible species in the genus Papillomavirus. A natural infection of horses causing papillomas on the nose and lips, but can be transferred to the skin. Causes papil-lomas experimentally in horses, but not in other species. Synonym horse papillomavirus. Cook RH and Olson C 1957 Am J Pathol 27, 1087 equine parvovirus A possible species in the genus Parvovirus. Isolated from the liver of an aborted equine fetus. Hemagglutinates guinea pig, rhesus monkey and fowl...

Parrot herpesvirus See psittacid herpesvirus

Parrot papillomavirus A possible member of the Papillomavirus genus, family Papovaviridae. Parry Creek virus PCRV An unassigned vertebrate rhabdovirus. Isolated from mosquitoes, Culex annulirostris, in Australia. Some antigenic relationship to members of the genus Lyssavirus. Not known to cause disease in humans. Calisher CH et al 1989 Intervirology 30, 241 parsimony stinginess, niggardliness, miserliness An approach to the construction of a phylogenetic tree that selects the phylogeny that...

Macropodid herpesvirus 2 MaHV2 An

Unassigned species in the subfamily Alphaherpesvirinae. Isolated from cultured cells of the dorcopsis wallaby, Dorcopsis muelleri luctuosa. The genome DNA is 135kb in length, G C 49.5 . Synonym dorcopsis wallaby herpesvirus. Johnson MA et al 1985 Arch Virol 85, 313 Johnson MA and Whalley JM 1987 Arch Virol 96, 153 mad cow disease A popular name for bovine spongiform encephalopathy BSE . Madin-Darby bovine kidney MDBK cells The first permanent cell line of a large domestic animal, derived from...

Snowshoe hare virus Sshv A strain of

California encephalitis virus in the genus Bunyavirus, belonging to the California serogroup. Originally isolated from the blood of an emaciated hare, Lepus ameri-canus, caught in Bitterroot Valley, Montana, USA. Isolated from lemmings, hares and mosquitoes in various parts of northern USA, Canada and Alaska. Antibodies found in humans and other animals. Distinguished from other members of the group by CFT, HAI or neutralization tests. Causes subclinical infection in humans. Gentsch J and...

Cercopithecine herpesvirus 4 CeHV4 An

Unassigned species in the family Herpesviridae. Isolated from a vervet monkey, Cercopithecus aethiops. Synonym SA15 virus. Malherbe H and Harwin RS 1963 S Afr Med J 37, 407 Cercopithecine herpesvirus 5 CeHV-5 A species in the genus Cytomegalovirus. Isolated from vervet monkey, Cercopithecus aethiops pygerythrus, kidney and salivary gland cell cultures. Focal lesions were observed in monolayer cultures. Giant cells and eosinophilic inclusion bodies were seen. Synonyms African green monkey...

S

S 1954-847-32 virus TURV A strain of Turlock virus in the genus Bunyavirus. SA virus A designation given to a virus isolated in hamster brain from nasal washings of a patient with a 'common cold'. A strain of parainfluenza virus type 5. Pathogenic for hamsters on i.c. injection. Antigenically identical to Simian virus SV5 and DA virus. Schultz EW and Habel K 1959 J Immun 82, 274 SA6 virus Synonym for cercopithecine her-pesvirus 3. SA8 virus Synonym for Cercopithecine herpesvirus 2. SA10 virus...

Moloney murine leukemia virus MoMLV

Obtained from mouse sarcoma S37. Produces lymphoid leukemia in 3-4 months. Most active when injected into newborn mice. Also causes leukemia in rats. Moloney murine sarcoma virus MoMSV A species in the genus Gammaretrovirus, belonging to the mammalian virus group. Isolated from a BALB c mouse injected with Moloney leukemia virus. A replication defective, acute transforming virus which rapidly induces sarcomas in mice and transforms cells in culture. Appears to...

Kadipiro virus Java7075 KDVJa7075 A

Kaeng Khoi virus KKV A tentative species in the genus Bunyavirus. Not assigned to an antigenic group. Isolated from bats and rats caught in caves in Thailand. Not reported to cause disease in humans. Kaffir-pox virus Synonym for Variola virus. Kaikalur virus KAIV A strain of Shuni virus, a species in the genus Bunyavirus, belonging to the Simbu serogroup. Isolated in suckling mice and from a pool of mosquitoes, Culex tritaeniorhynchus, collected at Kaikalur, Andra Pradesh, India. Not known to...

Rabok virus See Tanjong Rabok virus

Raccoon parvovirus RPV A species in the genus Parvovirus. raccoon papillomavirus A species in the genus Papillomavirus. During a field trial of vaccinia-rabies recombinant oral vaccine for raccoons, on Parramore Island, VA, USA, two of 53 live-trapped raccoons had papillomatous lesions of the skin. Papillomavirus antigens were detected in the skin lesions by immunohistochem-istry using a broadly cross-reactive rabbit polyclonal antibody. Hamir AN et al 1995 J Vet Diag Invest 7, 549 Raccoonpox...

Phalacrocoracid herpesvirus 1 PhHV

1 An unassigned species in the family Herpesviridae. Isolated on the CAM from a young little pied cormorant, Phalacrocorax melanoleucos. Other birds and rodents are resistant. No evidence of pathogenicity for cormorants. Replicates on the CAM, producing pocks. Synonyms cormorant herpesvirus 1 Lake Victoria cormorant herpesvirus. French EL et al 1973 Avian Pathol 2, 3 phasianid herpesvirus 1 Synonym for Gallid herpesvirus 1. phasianid herpesvirus 2 Synonym for Gallid herpesvirus 2.

Whitewater Arroyo virus WWAV A

Species in the genus Arenavirus discovered in 1995 in pack rats, Neotoma albigula, in New Mexico, USA. One of the New World arenaviruses. Associated with cases of human disease in California in 2000. whooping cough viruses Although there is no doubt that Bordetella pertussis is the major cause of whooping cough, viruses may sometimes cause a similar syndrome. Virus-associated cases are most common in England in the winter and the viruses incriminated most often are adenovirus, respiratory...

Anguillid herpesvirus 1 AngHV1 An

Unassigned herpes virus isolated from Japanese and European eels which grows in an eel kidney cell line, has typical her-pesvirus morphology, and induces syncytia and intranuclear inclusions. Has not been associated with morbidity or mortality in eels. Ueno Y et al 1992 Gyobyo Kenkyu 27, 7 Kobayashi T and Miyazaki T 1997 Fish Pathol 32, 89 Anhanga virus ANHV A tentative species in the genus Phlebovirus. Not serologically related to existing antigenic complexes of that genus. Isolated from the...

Goat herpesvirus CpHV1 Synonym for

Goat papillomatosis A natural infection of some herds, but not common the papil-lomas may become malignant. The virus has not yet been isolated. Moulton JE 1954 North Am Vet 35, 29 Goatpox virus GTPV A species in the genus Capripoxvirus. Clinically causes a disease similar to sheeppox, but the disease in goats takes a milder course. Causes focal epidermal lesions which proceed through papule, vesicle and pustule stages to scab formation. Lesions are usually on the udder, teats, scrotum, inside...

Dengue viruses 14 DENV14 Four

Serotypes of Dengue virus in the genus Flavivirus which together with Kedougou virus form the dengue virus serogroup. Double diffusion tests reveal a common antigen and specific antigens. Type 1 occurs in South-East Asia from India to Japan and Hawaii, with temporary spread to Greece, South Africa and Australia. The virus is not endemic in Japan except for a transient outbreak in the 1940s. Type 2 occurs in South-East Asia, central America and the Caribbean. Types 3 and 4 occur in Thailand and...

Pig rotaviruses See porcine rotavirus

Pig's blue eye disease Viral-induced disease of swine with characteristic corneal opacity accompanied by neurological, reproductive and respiratory alterations. See Porcine rubulavirus. Synonym La-Piedad-Michoacan-Mexico virus LPMV . pig-tailed macaque parvovirus A probable species in the genus Erythrovirus. Isolated from pig-tailed macaques Macaca nemest-rina with anemia following experimental immunosuppression. Green SW et al 2000 Virology 269, 105 pigeon adenovirus PiAdV A tentative species...

Homologous interference See interference

Homology The degree of relatedness between the nucleotide sequences of two nucleic acid molecules or the amino acid sequences of two protein molecules. Hybridization experiments can produce useful information but, for critical analyses, sequence data are needed. Hong Kong virus Synonym for Influenza A virus isolated in Hong Kong in 1968, which caused a global pandemic of Influenza A H3N2 infection. horizontal transmission Transmission between animals of any age after birth, usually excluding...

Bovine hemadsorbing enteric virus

Bovine herpes mammillitis virus Synonym for Bovine herpesvirus 2. Bovine herpesvirus 1 BoHV-1 A species in the genus Varicellovirus. A natural worldwide infection in cattle, but antibodies can also be found in mule deer, Odocoileus hemionus, and ferrets are susceptible to disease in the USA. Wild ruminants in Africa are probably the original host. The virus has also been isolated from soft-shelled ticks, Ornithodorus coriaceus, collected from mule deer in western USA, but it is not clear...

Liverpool vervet herpesvirus Synonym for

Ljungan virus LV An unassigned virus in the family Picornaviridae. May be a species in the genus Parechovirus. Isolated from bank voles, Clethrionomys glareolus, near the Ljungan river in Medelpad County, Sweden. Causes mild CPE without cell lysis in Vero or GMK cells. Particles are 27 nm diameter. Some sequence similarity is seen in the 5' non-coding region with mengo virus, and in other regions of the genome with echovirus 22. No firm link with disease in humans. Niklasson B et al 1999...

Lebombo virus 1 LEBV1 The only

Lechiguanas virus A strain of Andes virus in the genus Hantavirus, isolated from Oligoryzomys flavescens. Has caused human cases of hantavirus pulmonary syndrome. Le Dantec virus LeDV An unassigned species in the family Rhabdoviridae. With Keuraliba virus forms serogroup 4, the Le Dantec group. Isolated in Senegal from a girl with liver and spleen enlargement. Confined to W Africa save for rare exceptions a dock worker in Wales suffered a severe febrile illness after contracting Le Dantec virus...

Hydroxyethoxymethylguanine See acycloguanosine

Hydroxyphosphonylmethoxycytosine HPMPC An antiviral compound, also known as cidofovir, which appears to be active against several species of her-pesviruses. hyperchromic effect Increase in absorbance of light of wavelength 260nm by DNA at the melting point or transition temperature. hyperimmune serum Serum from an animal which has received two or more injections of a foreign antigen for the purpose of producing a reagent for use in serology. hypersensitivity A state of altered reactivity in...

Septicemia anserum exudative virus

Synonym for Derzsy's disease of geese, caused by Goose parvovirus. sequence The order of nucleotides in RNA or DNA or of amino acids in a polypep-tide. sequencing Determination of the sequence of nucleotides in a nucleic acid or of amino acids in a protein. See DNA sequencing, Sanger method, Maxam and Gilbert method and Edman degradation. serine-threonine kinase A cellular enzyme related to protein kinase C which is a target for several oncogenes, including Akt, Raf and Ras. Akt is the...

Exotic ungulate encephalopathy See prion diseases

Expressed genes The basic functional units of DNA, identified by cloning mRNAs and sequencing individual cDNAs. Also called ESTs or 'expressed sequence tags'. Martin KJ and Pardee AR 2000 Proc Natl Acad Sci 97, 3789 expression vector A cloning vector which expresses protein from genetically inserted foreign genes. The vector normally contains a strong promoter which is inducible and a strong initiation site for translation. Both eukaryotic and prokary-otic vectors can be used their suitability...

Walleye epidermal hyperplasia See percid herpesvirus

Walleye epidermal hyperplasia virus 1 WEHV-1 A species in the genus Epsilonretrovirus. Causes discrete epidermal hyperplasia on the skin of walleyes distinct from the diffuse epidermal hyperplasia caused by percid herpesvirus 1. The virus is distinguishable from Walleye dermal sarcoma virus by phyloge-netic analysis of the genome. Walleye epidermal hyperplasia virus 2 WEHV-2 A species in the genus Epsilonretrovirus. Causes discrete epidermal hyperplasia on the skin of walleyes. Nucleotide...

R

R61837 compound A drug that inhibits replication of rhinovirus by preventing virus uncoating, probably by binding to the virus capsid. Effective intranasally in clinical trials against human rhinovirus. R22 virus A strain of Seoul virus in the genus Hantavirus, isolated from Rattus norvegicus. R plasmid A bacterial plasmid containing a gene for drug resistance. rabbit calicivirus RCV A strain of Rabbit hemorrhagic disease virus in the genus Lagovirus. In contrast to RHDV, RCV appears to be...

Woodchuck herpesvirus marmota

Summers J et al 1978 Proc Natl Acad Sci 75, 4533 Woolly monkey sarcoma virus WMSV A species in the genus Gammaretrovirus. Isolated from a fibrosarcoma of a woolly monkey. Causes sarcomas on injection into marmosets. It is a transforming defective virus requiring simian sarcoma-associated virus as a helper to produce infective virus. The genome contains a single open reading frame encoding a single protein V-SIS, which is a fusion protein product of the virus env gene and the transduced c-sis...

Herpes gladiatorum herpes rugbeiorum

Herpes simiae virus Synonym for her-pesvirus B. herpes simplex viruses 1 and 2 There are two antigenic types herpes simplex type 1 is a synonym for Human herpesvirus 1 herpes simplex type 2 is a synonym for Human herpesvirus 2. herpes simplex virus group Synonym for the genus Simplexvirus. herpes venatorum Synonym for scrum-pox. Herpesviridae A diverse family of DNA viruses with characteristic morphology. Classification is based formally on genetic content. The virion is 100-200nm in diameter....