[235dimethyl2oxocyclohexyl2hydroxyethylglutarimide See cycloheximide

dimethyl sulfoxide (DMSO) Avery hygroscopic liquid with a slightly bitter taste and exceptional solvent properties for both inorganic and organic chemicals. Its penetrative properties have been used to aid the absorption of topically applied drugs such as idoxuridine. Widely used experimentally as a solvent for substances administered to cells in tissue culture.

diphasic milk fever Synonym for Tick-borne encephalitis virus.

diphenylamine reaction A chemical reaction that can be used for the colorimetric determination of DNA, e.g. the amount of DNA in a virus preparation. See orci-nol reaction.

Burton K (1956) Biochem J 62, 315

diploid A genome with two homologous genome sets. The only examples so far known amongst vertebrate viruses belong to the Retroviridae.

diplornavirus Double-stranded RNA virus. A name once proposed for the family Reoviridae.

disintegrations per minute (dpm)

disintegrations per minute (dpm) A direct measurement of radioactivity, estimated from the counts per minute measured in a radioactivity counter and the quenching of counts in the sample. 1|Ci gives 2.2 x 106dpm; 1 Becquerel is one disintegration per second.

disoxaril A compound that inhibits replication of enteroviruses and rhinoviruses by preventing uncoating.

Rossman MG and Rueckert RR (1987) Microbiol Sci 4, 206

dispersion factor A measure of the variability in incubation period (the interval from acquisition of infection to onset of illness). If the observed distribution of incubation periods is plotted on a logarithmic scale, the dispersion factor is the antilogarithm of the standard deviation.

disseminated intravascular coagulation (DIC) A serious blood disorder that has been associated with filovirus hemor-rhagic fever and also occurs in severe cases of congenital cytomegalic inclusion disease.

distemper virus Synonym for Canine distemper virus; hundestaupe; maladie de jeune age.

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