Abelson murine leukemia virus

(AbMLV) An acutely transforming strain of Murine leukemia virus in the genus Gammaretrovirus isolated from pred-nisolone-treated BALB/c mice inoculated with Moloney leukemia virus. It has a short latent period and produces lymphoid leukemia of B-cell type. It can transform 3T3 mouse cells in vitro. Requires a helper virus for complete virus replication.

Risser R et al (1982) Biochim Biophys Acta 651, 213

abl gene The oncogene of Abelson murine leukemia virus. The gene product, a 160 kDa fusion protein, attaches to the cell plasma membrane via a myristic acid residue and has tyrosine-specific protein kinase activity.

Abney virus A virus, isolated from an anal swab of a child with upper respiratory illness, which became a prototype strain of reovirus type 3.

Above Maiden virus

Above Maiden virus A serotype of Great Island virus in the genus Orbivirus.

abortive infection Infection in which some or all virus components are synthesized but no infective virus is produced. Also termed 'non-productive infection'. Usually occurs because the host cell is non-permissive. May also result from infection with defective viruses; in these cases it may be possible to rescue the virus by co-infection with a helper virus or by co-cultivation.

abortive transformation Transformation of cells which is unstable. A few generations after transformation the cells revert to normal.

Abras virus (ABRV) A strain of Patois virus. Isolated from Culex adamesi and C. paracrybda in Ecuador. Not reported to cause disease in humans.

Calisher CH et al (1983) Am J Trop Med Hyg 32, 877

Absettarov virus (ABSV) A strain of Tickborne encephalitis virus (Far Eastern subtype) in the genus Flavivirus. Isolated in 1951 in Leningrad from the blood of a 3-year-old boy with biphasic fever and signs of meningitis. Found in Sweden, Finland, Poland, former Czechoslovakia, Hungary, Austria, Bulgaria and western parts of the former USSR.

absorbance Amount of light absorbed by a solution or substance at a particular wavelength.

Synonym: optical density.

absorption Uptake of one substance by another, e.g. removal of antibodies from a mixture by adding soluble antigens, or vice versa.

absorption spectrum Graphical representation of absorbance of a substance at different wavelengths.

Abu Hammad virus (AHV) A strain in the genus Nairovirus belonging to the Dera Ghazi Khan serogroup. Isolated from a tick, Argas hermanni, in Egypt. Not reported to cause disease in humans.

Abu Mina virus (ABMV) A strain in the genus Nairovirus belonging to the Dera Ghazi Khan serogroup. Not reported to cause disease in humans.

Acado virus (ACDV) A serotype of Corriparta virus in the genus Orbivirus in the Corriparta serogroup. Isolated from

Culex antennatus and C. univittatus neavi in Ethiopia. Not reported to cause disease in humans.

Acara virus (ACAV) A possible species in the genus Bunyavirus, belonging to the Capim serogroup. Isolated from sentinel mice, Culex sp, and the rodent Nectomys squamipes in Para, Brazil and in Panama. Not reported to cause disease in humans.

Acatinga virus (ACTV) A probable species in the genus Orbivirus, isolated from phlebotomine sandflies in the Amazon region of Brazil. Antigenically related to Changuinola virus. Not reported to cause disease in humans.

acciptrid herpesvirus 1 (AcHV-1) An unas-signed virus in the family Herpesviridae, isolated from a nesting bald eagle, Haliaetus leucocephalus. Synonym: bald eagle herpesvirus.

Docherty DE et al (1983) Avian Dis 27, 1162

acetoxycycloheximide A glutarimide antibiotic. A potent reversible inhibitor of protein synthesis in animal cells. See also cycloheximide.

acetylcysteine A mucolytic agent used for adjunct therapy of bronchopulmonary disorders to reduce the viscosity of mucus. Appears to have antiviral effects in HIV patients due to inhibition of viral stimulation by reactive oxygen intermediates.

2,3-bis-(acetylmercaptomethyl)quinox-alin An antiviral agent. Inhibits poliovirus RNA synthesis in vitro and in vivo. Inhibits Human herpesvirus 1 multiplication in vitro. Does not interfere with attachment, penetration or DNA synthesis, but interrupts a late stage in virus assembly and/or maturation.

Bucchini D and Girard M (1975/76) Intervirology 6, 285

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