Avian enterolike virus 2 to 4 AELV2 to

Unassigned viruses in the family

Picornaviridae.

avian enteroviruses Include avian enceph-alomyelitis virus, duck hepatitis virus 1, duck hepatitis virus 3, and avian nephritis virus, as well as a number of strains isolated from normal birds.

avian erythroblastosis virus A mixture of viruses belonging to the genus Alpharetrovirus. Consists of a transforming virus and a leukemia virus which acts as helper for the defective transforming virus. The helper belongs to subgroup B of the chicken leukosis sarcoma viruses. The transforming virus is very closely related to the transforming component in avian myeloblastosis. Contains two transduced oncogenes: v-erbA and v-erbB. Expression of v-erbB, which is a homolog of the cellular epidermal growth factor receptor, is necessary and sufficient for induction of erythroblastosis. On i.v. injection into chickens the virus causes rapid erythroblastosis and anemia but on i.m. injection sarcomas are produced. Transforms fibroblasts and bone marrow cells in vitro. Non-producer cells can be obtained and the defective genome rescued by superinfection with a chicken leukosis sarcoma virus. The anemia and the occasional case of lymphatic leukemia produced are probably due to the helper virus. Synonym: erythroblastosis virus.

Graf T et al (1983) Cell 34, 7 Hayman MJ et al (1979) Virology 92, 31 Ishizaki R and Shimizu T (1970) Cancer Res 30, 2827

avian H10 influenza A virus An avian subtype, H10N4, of Influenza A virus which causes severe respiratory disease in mink (Mustela vison) both under field conditions and experimentally. Originally found to be the cause of a severe epidemic of respiratory disease in farmed mink in Sweden in 1984.

Englund L and Segerstad CH (1998) Arch Virol 143, 653

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