Bovine viral diarrhea virus 2 strain 890 A

strain of bovine viral diarrhea virus 2.

bovine viral diarrhea virus 2 C413 A strain of bovine viral diarrhea virus 2.

bovine visna-like virus Probably a species of the genus Lentivirus. Isolated from a cow with persistent lymphocytosis. Replicates in cultures of bovine embryonic spleen cells, with the slow formation of multinuclear giant cells similar to those produced by bovine syncytial virus. However, the two viruses differ morphologically and antigenically. Experimental infection of cows results in enlarged peripheral lymph nodes and hyperlymphocytosis. The disease may last over a year, during which time the virus can be re-isolated.

Georgiades JA et al (1978) J Gen Virol 311, 375 van der Maaten MJ et al (1972) J Natl Cancer Inst 49, 1649

Bowen's disease A pre-cancerous squa-mous cell carcinoma of the nail beds of humans which has been linked to infection with HPV 16.

box turtle virus 3 (TV3) A strain of Frog virus 3 in the genus Ranavirus.

Bozo virus (BOZOV) A serotype of Bunyamwera virus in the genus Bunyavirus. Isolated from the mosquito, Aedes opok, in Central African Republic. Not reported to cause disease in humans.

Saluzzo JF et al (1983) Ann Virol (Inst Pasteur) 134E,221

branched DNA assay A nucleic acid detection assay. A type of signal amplification assay performed in microtiter plates. RNA or DNA molecules released from virions are captured using specific probes bound to the surface of the plate. Branched DNA molecules are added to the well followed by an alkaline phos-phatase-linked synthetic probe which is detected by chemiluminescence, which is proportional to the concentration of target nucleic acid in the original specimen.

Brazil 2-4 virus An isolate of hantavirus from Rattus norvegicus in Brazil. Antigenically belongs to the Seoul serotype.

breakbone fever virus

breakbone fever virus Synonym for

Dengue virus.

Breda virus (BRV) See Bovine torovirus.

Breteau index A measure of the mosquito infestation rate used in arbovirology.

Breu Branco virus An unclassified virus isolated from Culicine mosquitoes in the Amazon region of Brazil. Not associated with disease in humans.

brilliant cresyl blue A photoreactive dye. See photodynamic inactivation.

Brivudin A halogenated nucleoside analog, bromovinyl deoxyuridine (BVDU) with a similar but less active inhibitory action against herpesvirus replication.

Descamps J et al (1982) J Virol 43, 332

Broadhaven virus (BRDV) A strain of Great Island virus in the genus Orbivirus, belonging to the Kemerovo serogroup.

Broad-range polymerase chain reaction

The use of a variety of primers to amplify genetic sequences in order to implicate a virus or group of viruses that may be involved in the etiology of a suspected viral disease. Priming sites that are conserved among a broad group of viruses are used initially, then more specific primers are used to positively identify the species involved.

bromelain A proteolytic enzyme isolated from pineapple stem which can be used to remove the peplomers from the surface of enveloped viruses such as influenza.

Compans RW et al (1970) Virology 42, 880

5-bromo-2-deoxyuridine A halogenated pyrimidine which can become incorporated into cellular DNA in place of thymidine. Incorporation may activate the transcription of viral RNA from genes integrated into the cellular DNA, such as those of Retroviridae.

bronchovirus syncytialis Synonym for Human respiratory syncytial virus.

brown bullhead papillomavirus A virus found in papillomas of the brown bullhead, Ictalurus nebulosus.

brown trout rhabdovirus Rhabdoviruses have been isolated from brown trout, Salmo trutta, in Finland and northern Italy, using a variety of fish cell lines. Detailed characterization has not yet been reported.

Koski P et al (1992) Bull Eur Assoc Fish Pathol 12, 177

Bruconha virus (BRUV) A strain of

Caraparu virus in the genus Bunyavirus belonging to the group C viruses. Isolated from mosquitoes, Culex (Melanoconion) sp.

Calisher CH et al (1982) Proc Int Symp Trop Arboviruses and Hemorrhagic fevers, Belem, Brazil, April 14-18,1980. Braz Acad Sci, p. 355

Brunswick bird plague virus A strain of avian influenza A virus.

Brus Laguna virus (BLAV) A virus in the genus Bunyavirus, belonging to the Gamboa serogroup. Isolated from mosquitoes, Aedeomyia squamipennis.

Calisher CH et al (1988) Am J Trop Med Hyg 39, 406

brushtail possum virus See possum papil-loma virus.

Bryan strain of Rous sarcoma virus A high-titer strain, highly oncogenic and much used in early experimental work. A defective virus which requires a helper avian leukosis virus for replication.

Sudol M et al (1986) Nucl Acid Res 14, 2391

BSC-1 (CCL 26) A continuous cell line from kidneys of the African green monkey, Cercopithecus aethiops. Develops characteristic CPE when infected with Simian virus 40. A valuable tool for viral diagnostic studies.

BT 4971 virus (PATV) A strain of Patois virus, in the genus Bunyavirus.

B-type inclusion body Inclusion bodies observed in the cytoplasm of vertebrate poxvirus-infected cells, representing sites of virus synthesis; characteristic of all productive poxvirus infections.

B-type virus particles A morphologically defined group of enveloped RNA virus particles seen typically outside the cells in mouse mammary carcinoma. They are always extracellular. They have a dense body or core (nucleoid) 40-60nm in diameter, contained within a membranous sac or envelope 90-120nm in diameter. The membrane is covered with protrusions. The nucleoid is usually eccentrically located within the envelope. Occasionally one envelope may contain more than one nucleoid. B-type particles bud through the cell membrane and contain an internal constituent morphologically indistinguishable from an A-type particle, which becomes the core. The prototype is Mouse mammary tumor virus.

Bernard W (1960) Cancer Res 20, 712 Dalton AJ (1972) J Natl Cancer Inst 49, 323

Bubaline herpesvirus 1 (BuHV-1) A species in the genus Varicellovirus. A herpesvirus isolated from water buffalo.

Brake F and Studdert MJ (1985) Aust Vet J 62, 331

budding A method of virus release from the cell in which replication has taken place. Occurs with many enveloped animal viruses. The viral ribonucleoprotein, with or without a surrounding membrane protein, associates with an area of the cell membrane which starts to form a coat around the virus protein. In electron micrographs it appears as a crescentic structure. The cell membrane closes around the virus and the particle leaves the cell. During the budding process, all cellular proteins in the area of membrane destined to become the virus coat are replaced by virus-coded proteins. Thus, in the mature virus particle, the envelope lipid is host cell-derived, but all proteins are virus-coded. The exact mechanism of this process is unknown.

budgerigar fledgling disease virus A poly-oma virus. See Budgerigar fledgling polyomavirus.

Budgerigar fledgling polyomavirus (BFPyV) A species in the genus Polyomavirus. Isolated from budgerigar embryo fibroblasts inoculated with tissues of affected birds. Also grown in chick embryo fibroblasts. Genome is double-stranded DNA, 5.1kb, circular, similar to other polyomaviruses.

Davis RB et al (1981) Avian Dis 25, 179

Lehn H and Müller H (1986) Virology 151,

31162

budgerigar parainfluenza virus A species in the genus Paramyxovirus. Isolated from caged budgerigars in Japan during an outbreak of severe enteritis. Similar to Newcastle disease virus but distinct from it and from Yucaipa virus. Synonym: Avian paramyxovirus 5.

Nerome K et al (1978) J Gen Virol 38, 293

Buenaventura virus (BUEV) A serotype of Punta Toro virus in the genus Phlebovirus. Isolated from Lutzomyia sp in Colombia.

buffalopox virus (BPXV) A species in the genus Orthopoxvirus. Causes occasional outbreaks of severe disease in India, and has been reported in Egyptian water buffalo. The pocks produced on the CAM are similar to those produced by Vaccinia virus, but they do not appear at temperatures above 38°C. Although some strains are obviously different from Vaccinia virus, many cases of clinical disease in buffaloes are caused by viruses that appear to be identical to it. Very similar to Lenny virus.

Synonym: vaccinia subspecies.

Baxby D and Hill BJ (1971) Arch Ges Virusforsch 35, 70

Tantawi HH et al (1977) J Egypt Vet Med Assoc 37, 15

Buggy Creek virus A serotype of Fort Morgan virus in the genus Alphavirus. Isolated from the bird nest bug, Oeciacus vicarius. Not associated with disease in humans.

Calisher CH et al (1988) Am J Trop Med Hyg 38, 447

Bu (IMR-31) cells (CCL 40) A line of near-diploid fibroblasts from male yearling buffalo, Bison bison. Finite life expectancy of at least 30 passages. Supports replication of a large number of viruses.

Buist bodies A synonym and probably the proper name for the elementary particles known as Paschen bodies seen in cells infected with smallpox or Vaccinia virus. The credit for their discovery is usually given to Paschen (1906), but Buist's account anticipates this by many years.

Buist JB (1886) Proc R Soc Edin 13, 603

Buistia pascheni A synonym proposed for Paschen bodies in order to commemorate the work of both Paschen and Buist. See Buist bodies.

Mackie TJ and van Rooyen CE (1937) Edin Med J 44, 72

Bujaru virus (BUJV) A species in the genus Phlebovirus, belonging to the sandfly fever group. With Munguba virus forms the Bujaru antigenic complex. Isolated from the rodent, Proechimys guyannensis oris, in Para, Brazil. Not known to cause disease in humans.

Bukalasa bat virus (BBV) A species in the genus Flavivirus. Isolated from bats of Tadarida sp in Uganda. Serologically a member of the Rio Bravo subgroup. No known arthropod vector.

Bunyamwera serogroup A group of more than 20 antigenically related viruses isolated from mosquitoes that are members of the genus Bunyavirus.

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