Chicken rotavirus 132 AvRVD132

Reoviridae. A strain of Rotavirus D, a species in the genus Rotavirus.

chick helper factor (chf) A probable species in the genus Alpharetrovirus. An endogenous avian leukosis virus of subgroup E, present in certain chicken cells. It can act as helper for a defective avian sarcoma virus by providing genetic information for the viral surface glycoproteins of the infectious progeny virus. Probably the same as RAV-60. See Avian leukosis virus.

Hanafusa H et al (1970) Proc Natl Acad Sci 66, 314

Chick syncytial virus (CSV) A species in the genus Gammaretrovirus, belonging to the Avian (Reticuloendotheliosis) virus antigenic group. Causes syncytia formation in some cell lines, and in young birds there is immunosuppression, and other syndromes such as abnormal feather development, bursal and thymic atrophy, and anemia. Less pathogenic than Reticuloendotheliosis virus. A replication-competent virus that does not carry an oncogene. Causes reticuloendotheliosis, splenomegaly and occasionally lymphomas in chickens.

Chikungunya virus (CHIKV) A species in the genus Alphavirus. Causes an epidemic disease in humans characterized by joint and back pains which are so severe that the patient is doubled up; hence the name, a Tanzanian word meaning 'that which bends up'. Incubation period 3-12 days. Onset sudden and the disease biphasic. Following 1-6 days' fever the temperature returns to normal for 1-3 days before the second period of fever which lasts a few days. In this phase a maculopapular pruritic rash on the trunk and limbs is common. After 6-10 days, recovery is usually complete although rarely joint pains may persist. Hemorrhagic fever-type disease may occur but shock is uncommon. Transmitted by various Aedes sp including A. furcifer, A. taylori, A. africanus and A. aegypti. Mansonia africana may also transmit the virus. No vertebrate host is known, but antibodies are present in monkeys, birds and many mammals. Occurs in India, South East Asia, eastern, western, central and southern Africa. Strains from Asia and Africa show some antigenic differences. Kills suckling mice on injection i.c; guinea pigs and rabbits show no signs of infection. Replicates with CPE in chick embryo, rhesus kidney and HeLa cell cultures.

Calisher CH (1999) Encyclopedia of Virology. Second edition, edited by A Granoff and RG Webster. London: Academic Press, p. 61 Chanas AC et al (1979) Arch Virol 59, 231

Chilibre virus (CHIV) A species in the genus Phlebovirus, isolated from sandflies. With Cacao virus forms the Chilibre virus antigenic complex. Isolated from insects of Lutzomyia sp in Canal Zone, Panama. Not reported to cause disease in humans.

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