Goose parvovirus

infectious nucleic acid Nucleic acid which is able to infect cells and initiate the production of complete virus particles. Nucleic acid removed from the virus particle is not protected from inactivation by tissue nucleases. It does not depend on cell receptors for attachment to, and ability to infect, cells and so may be able to infect species which the intact virus cannot. For example, human poliovirus nucleic acid injected i.c. in a mouse can initiate one cycle of infection. Complete virus is produced but cannot infect further cells. Infectious nucleic acid is readily isolated from viruses which do not require virion-contained enzymes to initiate replication.

Infectious pancreatic necrosis virus (IPNV) The type species of the genus Aquabirnavirus. The cause of an acute, contagious and highly lethal disease of a variety of salmonid fish including young rainbow trout in N America, Europe and Japan. Adult trout and salmon do not exhibit signs of infection but may become lifelong carriers. Infected young fish swim erratically and eventually die. There is necrosis of the pancreatic acinar and islet tissue. Experimentally, the virus causes pancreatic lesions in mice. Replicates in various fish cell cultures with CPE but not in mammalian cells. Virus has a single capsid structure, is 60nm in diameter, with 92 capsomeres and two pieces of double-stranded RNA, 3092 and 2784bp in length, with a 5' genome-linked protein (VPg) on each segment and no 3' poly A. Ether-resistant but acid-labile.

Dobos P and Roberts TE (1983) Can J Microbiol 29, 1377

Duncan R et al (1991) Virology 181, 541 Table I2. Strains of IPN virus

Infectious pancreatic necrosis virus DRT Infectious pancreatic necrosis virus Jasper Infectious pancreatic necrosis virus N1 Infectious pancreatic necrosis virus Sp infectious particle A virus particle that contains the complete viral genome and is capable of infecting a susceptible cell.

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