RR School Of Nursing

GSV See golden shiner reovirus

GU71U344 virus (GU344V) A serotype of Bushbush virus, in the genus Bunyavirus. Isolated from a sentinel hamster. Not known to cause disease in humans.

GU71U350 (GU350V) A serotype of Guajara virus, a species in the genus Bunyavirus.

Guajara virus (GJAV) A species in the genus Bunyavirus. Isolated from sentinel mice in Amapa and Para, Brazil. Not reported to cause disease in humans.

Guama serogroup viruses A group of sero-logically related viruses in the genus Bunyavirus. Isolated only in the Western Hemisphere.

Guama virus (GMAV) A species in the genus Bunyavirus belonging to the Guama serogroup. Isolated from sentinel monkeys and mice, rodents and bats. Mosquito-borne. Found in Brazil, Trinidad, Surinam, French Guiana and Panama. Can cause a febrile illness with arthralgia in humans.

Guanarito virus (GUAV) A species in the genus Arenavirus belonging to the South American hemorrhagic fever virus group. The cause of Venezuelan hemorrhagic fever. Causes a hemorrhagic fever in humans with a mortality rate from confirmed cases of 36%. The rodent vector is Zygodontomys brevicauda. Synonym: Venezuelan hemorrhagic fever virus.

Tesh RB et al (1993) Am J Trop Med Hyg 49, 227 Tesh RB et al (1994) Am J Trop Med Hyg 50, 452

guanidine hydrochloride Selectively inhibits replication of small RNA viruses in tissue culture. Antiviral activity is directed against genome-coded viral RNA polymerase. Picornaviruses become completely resistant after only a few passages in the presence of the drug.

Siegl G and Eggers HJ (1982) J Gen Virol 61, 111

guanidinium thiocyanate A powerful protein denaturant which is used to inhibit ribonuclease activity during RNA extraction from cells.

Chomczynski P and Sacchi N (1987) Anal Biochem 162,156

4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid A neuraminidase (sialidase) inhibitor which inhibits the growth in tissue culture of all nine neu-raminidase subtypes of avian Influenza A

viruses. A selective agent for the treatment (and prevention) of Influenza virus infections. Active against both Influenza A and Influenza B viruses. Delivered by inhalation for human use. A related drug which can be delivered orally is oseltamivir. Synonyms: 4-guanidino-Neu5Ac2en; GG167, zanamivir; Relenza,

Gubareva LV et al (2000) Lancet 355, 827 Hayden FG et al (2000) New Engl J Med 343,1282 von Itzstein M et al (1993) Nature 363, 418