Hepatitis GB viruses See GB viruses

herpes simplex viruses 1 and 2

hepatitis infectiosa canis virus Synonym for Canine adenovirus.

hepatitis non-A non-B virus In the mid-1970s, when diagnostic tests were established for Hepatitis A and Hepatitis B viruses, it became clear that much transfusion-related hepatitis was not caused by either virus. The term 'non-A non-B' was used together with a diagnosis of exclusion to describe the agent(s) responsible for this disease. See Hepatitis C, E, F, G and GB viruses.

hepatocytes Epithelial liver cells.

hepato-encephalomyelitis virus Prototype strain of reovirus type 3, isolated in Sydney, Australia in 1953 from a child with bronchopneumonia, alopecia and conjunctivitis.

Stanley NF et al (1953) Aust J Exp Biol Med Sci 31, 147

Hepatovirus A genus in the family Picornaviridae comprised of one species: Hepatitis A virus, with two strains, human hepatitis A virus and simian hepatitis A virus. There is one tentative species in the genus, avian encephalomyelitis-like virus. Virions are stable, resistant to acid pH and elevated temperatures. There are a large number of strains of Hepatitis A virus which differ by less than 20% in genome RNA sequence homology, but there is little sequence similarity with other picornaviruses. The viruses cause hepatitis and gastroenteritis, with fever, jaundice, abdominal pain and occasional diarrhea. Persistent infection does not occur in vivo, and the viruses are not associated with chronic hepatitis. There is an excellent vaccine for prevention of human hepatitis A virus infection. See Hepatitis A virus.

Hep-G2 cell line A human hepatocyte carcinoma cell line established from a 25-year-old male Caucasian.

Hep-2 cells (CCL 23) A heteroploid cell line derived from tumors produced in irradiated and cortisone-treated weanling rats after injection with epidermoid carcinoma tissue from the larynx of a 56-year-old human male.

HEPT 1[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine. Reported to be a specific inhibitor of Human immunodeficiency virus type 1 replication.

Baba M et al (1989) Biochim Biophys Res Commun 165, 1375

Heron hepatitis B virus (HHBV) A species in the genus Avihepadnavirus. Discovered in 1988 in sera of grey herons, Ardea cinerea, from Germany. Shares sequence homology with Duck hepatitis B virus (overall about 78%) but differs in that a highly conserved open reading frame is present upstream of C in a position analogous to the X gene of ortho-hepadnaviruses, and the S protein and not the L protein possesses a potential myristylation site. The virus does not infect ducks, but in the grey heron it infects the liver and produces a viremia. In one survey about 30% of herons in Germany were infected, but little is known of the worldwide incidence and distribution.

Netter HJ et al (1997) J Gen Virol 78,1707

herpangina A short febrile illness with sore throat, chiefly affecting young children in the summer in which there are small papules or vesicles around the fauces, which soon break down into shallow ulcers. Dysphagia, fever, vomiting and prostration may occur. Classically caused by coxsackie A viruses, particularly types 1-6, 8, 10 and 22. Sporadic cases have been associated with coxsackie viruses A7, A9, B1-5 and echoviruses 6, 9, 16 and 17.

herpes ateles 2 Synonym for Ateline her-pesvirus 2.

herpes febrilis Synonym for Human her-pesvirus 1 or 2.

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