Homologous interference See interference

homology The degree of relatedness between the nucleotide sequences of two nucleic acid molecules or the amino acid sequences of two protein molecules. Hybridization experiments can produce useful information but, for critical analyses, sequence data are needed.

Hong Kong virus Synonym for Influenza A virus isolated in Hong Kong in 1968, which caused a global pandemic of Influenza A (H3N2) infection.

horizontal transmission Transmission between animals of any age after birth, usually excluding via the maternal milk.

'horse colds' An old name for equine influenza.

horse papillomavirus Synonym for equine papillomavirus.

horsepox virus A species in the family Poxviridae. Causes papular lesions on lips, buccal mucosa and sometimes in the nose with fever and drooling of saliva. Only a few deaths. Course 10-14 days or 3-4 weeks in severe cases. May be transmissible to humans; finger lesions have been horsepox virus

reported in those working with horses. Not now present in the UK. See also grease-heel virus.

Synonyms: contagious pustular dermatitis of horses virus; contagious pustular stomatitis of horses virus.

horseradish peroxidase An enzyme derived from the horseradish plant, Armoracia rusticana. Used in ELISA tests to give the color reaction with its substrate, e.g. brown with 3',3'-dianisidine.

host cell A cell in which a virus is replicating.

host range A listing of species of hosts which are susceptible to a given virus (or other pathogen).

hot spot A site within a gene at which mutations occur with unusually high frequency.

HR80-39 virus A strain of Seoul virus in the genus Hantavirus, isolated from rats.

HSDM1C1 cells (CCL 148) A cell line derived from the parental HSDM1 line that secretes and synthesizes large quantities of prostaglandin E2 (PGE2).

Hs888Lu cells (CCL 211) A fibroblast-like cell line derived from the normal lung tissue of a 20-year-old Caucasian male with osteosarcoma metastatic to the lung.

Hsiung Kaplow herpesvirus Synonym for caviid herpesvirus 1.

HT-1080 cells (CCL 121) A cell line established from a fibrosarcoma arising adjacent to the acetabulum of a 35-year-old Caucasian male.

HT virus A strain of H1 virus in the genus Parvovirus. A rodent parvovirus of sero-logical group 2. Antigenically related to but not identical with H1 virus. Shows equal avidity for guinea pig and hamster erythrocytes, but does not react with those of humans or rats.

HTDV Human teratocarcinoma-derived virus. See human endogenous retroviruses.

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