Intramuscular immunoglobulin IMIG

A generally effective technique for preexposure prophylaxis against hepatitis A. The availability of a killed Hepatitis A virus vaccine has reduced the need for IMIG especially in developed countries.

intraneuronal spread The movement of viruses such as herpes simplex or rabies through neurons.

intrathecal antibodies Virus persistence in the CNS is usually accompanied by long-lasting intrathecal antibody synthesis with specificity for viral proteins. Selection and recruitment of these antibodies to the CNS can be detected in the CSF as a restricted oligoclonal pattern that can be used as a diagnostic marker.

Felgenhauer K and Reiber H (1992) Clin Invest 70,28

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