Latent rat virus See Kilham rat virus

lateral body A structure seen by electron microscopy of vertebrate poxvirus particles. The core of the particles appears to be biconcave with two lateral bodies in the concavities. The function of lateral bodies is not known.

Lates calcarifer encephalitis virus A species in the genus Betanodavirus, causing behavioral abnormalities and encephalitis in juvenile barramundi in Australia.

Munday BL et al (1994) Aust Vet J 71, 384

latex agglutination A serological test in which antibody or antigen is adsorbed on to polystyrene latex beads which are then incubated with the other reactant. Positive reactions show as aggregates of latex particles that can be detected readily by the naked eye.

Latino virus (LATV) A species in the genus Arenavirus. Belongs to the Tacaribe serogroup. Isolated from a rodent, Calomys callosus, in Bolivia and Brazil. Not reported to cause disease in humans.

LAV See Lymphadenopathy-associated virus and Human immunodeficiency virus.

LC-540 cell line (CCL 43) A steroid-secreting cell line from a transplantable Leydig cell tumor which arose spontaneously in the testes of an adult male rat.

LCDV-1 Synonym for Lymphocystis disease virus 1 (flounder virus).

LCDV-2 Synonym for lymphocystis disease virus 2 (Dab lymphocystis disease virus).

LCMV Synonym for Lymphocytic chorio-meningitis virus.

leader sequence A sequence of nucleotides at the 5' end of a mRNA molecule which precedes the AUG initiation codon. The leader is an untranslated segment of mRNA that varies in length in different viruses. A leader sequence is also found in the virion RNA of negative strand viruses, such as rhabdoviruses.

leaky mutants Mutants which do not conform completely to the mutant characteristic: they have residual activity under the non-permissive condition. For example, a temperature-sensitive mutant which has some activity at the restrictive temperature.

Leaky virus A possible species in the genus Hantavirus. Isolated from mice, Mus mus-culus, in North America. Not known to cause disease in humans.

Puthavathan P et al (1993) Virus Res 30, 161

Leanyer virus (LEAV) A tentative species in the genus Bunyavirus, isolated from mosquitoes in Northern Australia in 1974. Not known to cause disease in humans.

Stuckley KG and Wright PJ (1983) Aust J Exp Biol Med Sci 61, 193

Lebombo virus (LEBV) A species in the genus Orbivirus, the only member of the Lebombo virus group. Isolated from a rodent, Thryonomys swinderianus, and from mosquitoes, Mansonia africana, in Nigeria and Aedes circumluteolus in S Africa. The virus was also isolated from a child in Ibadan, Nigeria in 1968.

Moore DL et al (1975) Ann Trop Med Parasitol 69, 49

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