unassigned species in the subfamily Alphaherpesvirinae. Isolated from cultured cells of the dorcopsis wallaby, Dorcopsis muelleri luctuosa. The genome DNA is 135kb in length, G+C 49.5%. Synonym: dorcopsis wallaby herpesvirus.
Johnson MA et al (1985) Arch Virol 85, 313 Johnson MA and Whalley JM (1987) Arch Virol 96, 153
mad cow disease A popular name for bovine spongiform encephalopathy (BSE).
Madin-Darby bovine kidney (MDBK) cells The first permanent cell line of a large domestic animal, derived from the kidney of a normal adult steer in 1957.
Madin SH and Darby NB (1958) Proc Soc Exp Biol Med 98, 574
Madin-Darby canine kidney (MDCK) cells An epithelial-like cell line established from the kidney of a normal cocker spaniel in 1958. Widely used for virus growth studies, including primary isolation of human influenza viruses. See MDBK (NBL-1) cells.
mad itch virus Synonym for pseudorabies virus.
Madrid virus (MADV) A species in the genus Bunyavirus, belonging to the group C serogroup. Isolated from a man with a febrile illness in Panama. Also isolated from sentinel mice in the same area, the mosquito, Culex vomerifer, and the spiny rat, Proechimys semispinosus. Antibodies found in 3 of 96 humans but no further cases of disease reported.
MADT (morphological alteration and disintegration test) An electron microscopy-based assay for testing for chemical inactivation of Hepatitis B virus.
Prince DL et al (1993) J Clin Microbiol 31,3296
maedi-visna virus (Icelandic: maedi = dyspnea) See Visna/maedi virus.
Maguari virus (MAGV) A serotype of Bunyamwera virus in the genus Bunyavirus. Isolated from sentinel mice and mosquitoes in Brazil and from a horse in Guyana. Present also in Trinidad, Colombia and Argentina. Antibodies found in cattle, sheep and birds. Not reported to cause disease in humans.
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