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p2b-2 virus A strain of Tacaribe virus in the genus Arenavirus.

P4 laboratory An old name for a high containment laboratory designed for safe work with viruses that cause serious human disease for which no vaccines or other treatment are available (e.g. Ebola virus, Lassa fever virus) and thus present a serious hazard to the laboratory worker. Now referred to as a BSL4 (Biosafety level 4) laboratory.

p53 A multifunctional protein which plays a role in modulating gene transcription, control of the cell cycle, activating apop-tosis, controlling DNA replication and repair, and maintaining genomic stability and tumor suppression. Several groups of oncogenic viruses (adeno-viruses, SV40 and papillomaviruses) produce proteins that interact with and inactivate p53 to cause cell transformation and neoplasia.

Elledge RM and Lee W-H (1995) BioEssays 17, 923

Levine AJ (1993) Annu Rev Biochem 62, 623 Liebermann DA et al (1995) Oncogene 11, 199

p360 virus (P360V) A strain of Puumala virus in the genus Hantavirus. Isolated from a human case of hemorrhagic fever with renal syndrome (HFRS) in western Russia. Phylogenetic analysis showed it to be related to Puumala virus; the probable rodent host is the vole, Clethrionomys glareolus, from which a closely similar isolate was made.

13p2 virus Synonym for American oyster reolike virus.

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