Polka fever virus See dengue viruses

poly A Polyadenylic acid. A stretch of polyadenylic acid up to 300 bases long occurs at the 3' end of eukaryotic cell mRNA (histone mRNA is an exception) and of most virus mRNAs which have been studied, including the virion RNA of most positive-strand viruses. It is believed to increase the stability of mRNA by making it more resistant to nuclease digestion.

polyadenylation The addition of adenylate residues, usually to the 3' end of RNA molecules.

poly A polymerase An enzyme which adds adenylate residues to the 3' end of RNA.

poly AU

poly AU A synthetic double-stranded polynucleotide. Under the influence of polynucleotide phosphorylase, adeno-sine diphosphate molecules polymerize to form a polyribonucleotide containing only adenine bases. This is usually referred to as 'poly A'. Similarly, using uridine diphosphate, poly U can be obtained. If equimolar amounts of poly A and poly U are mixed in dilute aqueous solution they form a complex in which the adenine and uridine bases link together to make a double strand, known as 'poly AU'.

poly C Polycytidylic acid. A stretch of poly-cytidylic acid about 100 nucleotides long, of unknown function, is found in the genome RNA of some picornaviruses.

polycistronic messenger RNA A mRNA which contains the coding sequences for two or more proteins.

polyclonal antibody A preparation containing antibodies against more than one epitope of an antigen.

Polydnaviridae A family of viruses affecting invertebrates whose genome has multiple double-stranded DNAs of variable size and which infect parasitic wasps in which the viral genome is integrated within the wasp genome.

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