Porcine adenovirus 15 PadV1 to 5 An

original serotype classification of porcine adenoviruses. Now porcine adenoviruses 1-3 are Porcine adenovirus A, 4 is Porcine adenovirus B, and 5 is Porcine adenovirus C.

Porcine astrovirus (PastV) A species in the genus Astrovirus. There is a single serotype, porcine astrovirus 1 (PastV-1). Isolated from pigs with gastroenteritis. The virus grows in a porcine embryonic kidney cell line.

Shimizu M et al (1990) J Clin Microbiol 28, 201

Porcine circovirus 1 and 2 (PCV-1 and PCV-2) Species in the genus Circovirus, PCV-1 was first isolated in Germany in 1974 from a persistently infected PK15 cell line. The DNA genome is 1.76kb in length. Does not cross-react antigenically or by DNA sequence homology with avian circovirus species (e.g. Beak and feather disease virus or chicken anemia agent). Of various species tested, only domestic pigs, minipigs and wild boar were found to have antibodies to the virus, which appears to be widespread in pigs in Europe and North America. An antigenically distinct serotype (PCV-2) was isolated in France in 1997 from young pigs with wasting disease and is associated with a newly recognized disease known as post-weaning multi-systemic wasting syndrome (PMWS). Pigs with PMWS show debility, dyspnea, palpable lymphadenopathy, diarrhea, and pallor or icterus. The lesions can be reproduced experimentally in piglets, though their full expression may involve co-infection with Porcine parvovirus or PRRS virus. There is only about 80%

homology between the genomes of PCV-1 and PCV-2. The precise genetic and phenotypic characteristics of these two circoviruses, and whether more than one virus is involved in disease causation requires further investigation.

Allan GM and Ellis JA (2000) J Vet Diagn Invest 12, 3

Meehan BM et al (1998) J Gen Virol 79, 2171 Niagro FD et al (1998) Arch Virol 143, 1723

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