possible species in the genus Orthopoxvirus, isolated in 1974 from the kidneys of a wild big gerbil, Rhombomys opimus, caught in Turkmenia. It resembles Cowpox virus and carnivora poxviruses but was markedly different from Ectromelia virus. Apparently identical to viruses isolated from Felidae in Moscow Zoo. Experimental infection of the natural hosts, big gerbil, and yellow suslik, Citellus fulvus, caused severe disease and high mortality. Transmission between cage mates occurred. Virus is present in urine for at least 3 weeks and in kidneys for at least 5 weeks.
Marennikova SS et al (1978) Arch Virol 56, 7
rolling circle A model for DNA replication which involves a circular intermediate molecule. One strand remains as a circular template and may be copied repeatedly but the other parental strand is only copied once, so replication is asymmetric.
Gilbert W and Dressler D (1968) Cold Spring Harbor Symp Quant Biol 33, 473
Rondonia virus A probable strain in the genus Phlebovirus, isolated in Samuel, Rondonia State, Brazil, from phle-botomine sandflies in 1988. Not associated with human disease.
roseola infantum Synonym for exanthem subitum. A childhood disease appearing rarely before 6 months of age and usually before age 4 years sporadically or in limited size outbreaks. There is an exanthema preceded by a fever that subsides with the appearance of a macular-papular rash on the trunk and to a lesser extent on the face and extremities. Rarely persists more than 24 h. Caused by Human herpesvirus 6 in the genus Roseolovirus.
Roseolovirus A genus in the subfamily Betaherpesvirinae. Viruses are isolated from lymphocytes and have a unique DNA structure. There are two species in the genus, Human herpesvirus 6 which causes roseola infantum (also called exanthem subitum or sixth disease), and Human herpesvirus 7 which has not so far been clearly associated with a human disease. There are two variants of HHV6, HHV-6A and HHV-6B, and only HHV6-B has been clearly associated with roseola infantum.
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