Sapporo virusSapporo HuSLVSV1982

JP) A strain of Sapporo virus in the genus 'Sapporo-like viruses'.

Saquinavir A licensed antiviral drug, an inhibitor of the HIV protease, also known as Ro31-8959. Extremely active inhibitor of HIV replication in cell culture. A pep-tide-based transition state mimetic of the protein cleavage site. Synonym: Invirase.

Roberts NA et al (1990) Science 248, 358 Srinivas RV and Fridlund A (1999) In Encyclopedia of Virology, Second edition, edited by A Granoff and RG Webster. London: Academic Press, p. 778

Saraca virus (SRAV) A serotype of Changuinola virus in the genus Orbivirus. Isolated from Lutzomyia sp in Oriximina, Brazil. Not reported to cause disease in humans.

sarcoma viruses Sarcoma viruses have been isolated from a number of species of birds and mammals but the most extensively studied are the fowl, mouse and cat viruses. Since they contain a transduced cellular oncogene, one of the virus genes is usually absent or nonfunctional, so they are generally defective and require a helper leukemia virus for replication. They transform cells in culture and produce infective virus if a helper virus is present. Sarcomas are produced on injection into animals, usually after a short latent period of a few days. Some tumors spontaneously regress.

sarkosyl

sarkosyl A detergent used to break up virus particles, or infected cells.

satellite RNAs Small RNA molecules found in some plant viruses which may resemble viroids but can only replicate in the presence of a helper virus. Also called 'virusoids'.

Francki R (1986) Annu Rev Microbiol 39, 151

satellite virus An absolutely defective virus which, in nature, depends on the presence of a helper virus to provide some factor necessary for its replication. See Adeno-associated virus.

Sathuperi virus (SATV) A species in the genus Bunyavirus, belonging to the Simbu serogroup. Isolated from mosquitoes in Madras, India, and Ibadan, Nigeria. Also isolated from cattle. Not reported to cause disease in humans.

Saumarez Reef virus (SREV) A species in the genus Flavivirus belonging to the Tyuleniy virus serogroup. Isolated from sea bird ticks, Ornithodoros capensis, collected from the nests of sooty terns on islands off the coast of Queensland, Australia and Ixodes eudyptidis from dead silver gulls in northern Tasmania. Antigenically most closely related to Tyuleniy virus. Causes paralysis on i.c. injection in newborn mice. Not known to cause disease in humans, or other animals.

St George TD et al (1977) Aust J Exp Biol Med Sci 55, 493

sawgrass virus (SAWV) An unassigned species in the family Rhabdoviridae, belonging to the Sawgrass serogroup. Isolated from the eastern dog tick, Dermacentor variabilis, and the rabbit tick, Haemaphysalis leporis-palustris, in Florida, USA. Antigenically related to New Minto virus and Connecticut virus. Not reported to cause disease in humans.

Ritter DG et al (1978) Can J Microbiol 24, 422

scabby mouth virus Synonym for Orf virus.

Scandinavian epidemic nephropathy virus Synonym for Puumala virus.

Schwarz virus A strain of Edmonston B measles virus that was further attenuated by multiple passages in chick embryo fibroblast cells and licensed for use as a live measles vaccine in 1965. Used in many parts of the world as the measles vaccine component. Closely similar genetically to Moraten virus.

Rota JS et al (1994) Virus Res 31, 317 Schwarz AJF (1962) Am J Dis Child 103, 256

sciurid herpesvirus 1 (ScHV-1) An unas-signed species in the subfamily Betaherpesvirinae. Seventeen of 81 European ground squirrels, Citellus citel-lus, trapped in the Timisoara area of Romania were found to have typical cytomegalovirus inclusion bodies in their salivary gland cells. These animals appeared to be in good health. Cultures of the salivary gland cells developed foci of round refractile cells after 4 days, and in 10 days these spread to involve half the culture. The virus could not be passaged in mouse, rat or human cultures. Synonyms: ground squirrel cytomegalo-virus; European ground squirrel cytomegalovirus; American ground squirrel herpesvirus.

Barahona HH et al (1975) Lab Anim Sci 25, 725 Diosi P and Babusceac L (1970) Am J Vet Res 31, 157

Diosi P et al (1967) Arch Ges Virusforsch 20, 383

sciurid herpesvirus 2 (ScHV-2) An unas-signed virus in the family Herpesviridae. Isolated from a spontaneously degenerating primary kidney cell culture from a N American species of ground squirrel, Citellus citellus, in which it is a latent infection. Kills suckling mice on injection i.c. Produces pocks on the CAM. Replicates well in rabbit, hamster, marmoset and owl monkey cells, but poorly in dog fetal lung and Vero cells. Virus is readily released from cells. Neutralized by herpesvirus snaguinus antiserum but there is no reciprocal neutralization. Not neutralized by antiserum to sciurid herpesvirus 1.

Synonym: ground squirrel herpesvirus.

Barahona HH et al (1975) Lab Anim Sci 25, 735 Diosi P et al (1975) Pathol Microbiol 42, 42

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