Simian Tlymphotropic virus 13 STLV1

to -3) Strains of Primate T-lymphotropic viruses 1-3, species in the genus Deltaretrovirus. STLV isolates have been made from various non-human primate species including Japanese macaque, pig-tailed macaque, bonnet macaque, stump-tailed macaque, Taiwanese macaque baboon, African green monkey, tantalus monkey and chimpanzee. The viruses from African monkeys and chimpanzees are closely related genetically (more than 95% sequence homology) to human T-lymphotropic virus 1 (HTLV-1) whereas the Asian STLV strains are only 90% related genetically to Asian HTLV-1

strains. Two more distantly related STLV isolates have been made, from a bonobo, Pan paniscus, and a baboon, Papio hamadryas, from Eritrea. The latter isolate was called STLV-PH 969, and both isolates appear more closely related genetically to HTLV-II rather than HTLV-I. Because it is difficult to distinguish the STLVs and HTLVs genetically, the species name is now Primate T-lym-photropic virus 1, 2 and 3. Leukemia has not been observed in the monkeys from which STLV isolates were made.

van Brussel M (1996) J Gen Virol 77, 347 Yanigahara R (1994) Adv Virus Res 43, 147

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