Swine vesicular disease virus SVDV A

porcine variant of human coxsackie virus B5, a serotype of Human enterovirus B in the genus Enterovirus. Swine vesicular disease was first observed in Italy in 1966. Subsequent outbreaks occurred in Hong Kong in 1971, Europe and Japan in 1972-75. There are several antigenically different strains of the virus. Infectivity can be neutralized by human coxsackie B5 antiserum but the viruses can be distinguished by immunodiffusion, neutralization and RNA hybridization. Causes a disease similar to foot-and-mouth disease in pigs. Fever and vesicular lesions on the feet and snout. Replicates with CPE in pig kidney cell cultures. Injected i.c. in newborn mice causes paralysis and death in 5-10 days. Donkeys, cattle, rabbits, guinea pigs and chickens develop no disease on exposure to virus. Laboratory infections in humans with aseptic meningitis are reported. Coxsackie B5 injected into pigs does not cause disease.

Seechurn P et al (1990) Virus Res 16, 255

swine vesicular exanthema virus Synonym for Vesicular exanthema of swine virus.

swollen baby syndrome A syndrome with widespread edema, abdominal distension and bleeding seen in children in

Liberia in response to Lassa fever virus infection.

Monson MH et al (1987) Am J Trop Med Hyg 36, 408

Symmetrel™ Trade name for amantadine hydrochloride as 100mg capsules.

syncytial viruses Viruses which in cell cultures induce the formation of syncytia. These include bovine, hamster, human, feline and simian species belonging to the genus Spumavirus as well as other viruses such as respiratory syncytial virus, her-pesvirus and Measles virus, which also induce syncytia. Often used as an alternative name for foamy viruses.

Loh PC (1993) In The Retroviridae, vol. 2, edited by JA Levy. New York: Plenum Press, p. 361

syndrome A group of symptoms or signs which together characterize a disease.

0 0

Post a comment