Transmissible gastroenteritis of pigs virus

Synonym for Transmissible gastroenteritis virus.

Transmissible gastroenteritis virus (TGEV)

A species in the genus Coronavirus, with worldwide distribution. Causes a commonly fatal disease of young pigs and occasionally has infected dogs. There is diarrhea, vomiting, dehydration and death after 5-7 days. In pigs over 3 weeks there is more chronic diarrhea but recovery is usual. Virus replicates in the small intestine and can be demonstrated in the feces by electron microscopy. Infectivity survives drying at room temperature for 3 days. Spread by direct and indirect contact: starlings may play a role in the mechanical spread. Replicates in pig kidney cell cultures. An inactivated vaccine prepared in dog cell cultures has been used. Colostrum from recovered sows protects the young. There appears to be only one antigenic type. Synonyms: transmissible gastroenteritis of pigs virus; porcine respiratory corona-virus.

Horzinek MC et al (1982) Infect Immun 37, 1148 Pensaert MB et al (1986) Vet Quart 8, 257

transmissible mink encephalopathy virus The same as or a variant of scrapie virus. Present in mink brain tissue and infectivity will survive storage in 10% neutral formalin. On injection into mink causes progressive neurological disease after an incubation period of 6 months. See also prion diseases.

Chesebro BW (editor) (1991) Transmissible spongiform encephalopathies. Curr Top Microbiol Immun 172, 208 pp

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