TVX virus See Tumor virus X

Twinrix A combination of vaccine for protection against Hepatitis A and B viruses.

two-dimensional electrophoresis A technique in which the constituents of a sample are separated by electrophoresis in one dimension on one property and in a second dimension, usually at right angles to the first, on another property. It is used to resolve complex mixtures of molecules.

Ty elements Transposable elements of the yeast Saccharomyces cerevisiae.

Tyuleniy virus (TYUV)

type A virus particles See A-type virus particles.

type B oncovirus group See Betaretrovirus.

type B virus particles See B-type virus particles.

type C oncovirus group See Gammaretro-virus.

type C virus particles See C-type virus particles.

type D virus particles See D-type virus particles.

type-specific antigen An antigen which defines a particular virus serotype, normally on the basis of a neutralization test.

Tyuleniy virus (TYUV) A species in the genus Flavivirus, a member of the Seabird tick-borne virus group. Isolated from a tick, Ixodes putus, collected from rifts in the rocks on Tyuleniy Island, Patience Bay, south-east of Sakhalin Island, in the north of the former Soviet Far East, where there is a colony of guillemots, Uria aalge. Has also been isolated from Ixodes uriae collected in Three Arch Rocks National Wildlife Refuge, on the Oregon coast, USA and from Ixodes putus collected from pelagic cormorants, Phalacro-corax pelagicus, on the Commodore Islands. Pathogenic for suckling mice i.c. and i.p. but kills adult mice only on i.c. injection. Replicates with CPE in pig kidney cell cultures. Antibodies are found in humans, fur seals and several species of birds. The mosquito, Aedes aegypti, can be infected experimentally. Not reported to cause disease in humans.

Lvov DK et al (1972) Arch Ges Virusforsch 331, 139

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