Whitewater Arroyo virus WWAV A

species in the genus Arenavirus discovered in 1995 in pack rats, Neotoma albigula, in New Mexico, USA. One of the New World arenaviruses. Associated with cases of human disease in California in 2000.

whooping cough viruses Although there is no doubt that Bordetella pertussis is the major cause of whooping cough, viruses may sometimes cause a similar syndrome. Virus-associated cases are most common in England in the winter and the viruses incriminated most often are adenovirus, respiratory syncytial virus, parainfluenza and Influenza virus types A and B.

WI-26 VA4 cells (CCL 95.1) This cell line is an SV40 virus-transformed derivative of WI-26 cells, a human diploid cell line established from the embryonic lung tissue of a male Caucasian.

WI-38 cells (CCL 75) A diploid cell line derived from normal female embryonic lung tissue. Has one of the broadest spectra for human viruses of any cell line tested, and is particularly useful in the isolation of rhinoviruses. Has been used for the preparation of a number of human virus vaccines. Synonym: Wistar Institute 38 cells.

WI-1003 cells (CCL 154) One of several fibroblast-like strains derived from human adult lungs.

wildebeest herpesvirus Synonym for Alcelaphine herpesvirus 1.

wild strains Isolations made from naturally infected hosts. Such strains may be different from laboratory strains. See vaccine virus markers.

wild-type The reference or original genotype, used for comparison with mutant or laboratory-adapted strains which have arisen from it.

WIN-54954 An antiviral drug developed to bind to the hydrophobic pocket in VP1 of picornaviruses and inhibits their replication. See pirodavir.

windpocken Synonym for chickenpox. See Human herpesvirus 3.

winter vomiting disease virus A better name is 'acute epidemic gastroenteritis virus' as diarrhea may be as important a symptom as vomiting which may be absent, and the winter season is not a well-documented feature.

wish cells (CCL 25) A heteroploid human amnion cell line derived from colonies of 'altered' cells which appeared after the primary cell culture had been passaged 35 times. Has been used to differentiate virulent from avirulent strains of Measles virus.

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