X

X14 virus A species in the genus Parvovirus. A rodent parvovirus of group 1. Isolated from mammary tissue of a Sprague-Dawley rat treated with X-rays and methylcholanthrene. Resembles latent rat virus in biological properties. See Tumor virus X.

Payne FE et al (1964) Virology 23, 109

Xaraira virus A possible species in the genus Orbivirus, isolated from phle-botomine sandflies in the Amazon region of Brazil. Antigenically related to Changuinola virus. Not associated with disease in humans.

XC cells (CCL 165) A cell line derived from a transplantable tumor which was induced in newborn outbred Wistar rats by the intramuscular injection of the Prague strain of Rous sarcoma virus.

Xenopus virus T21 (XV-T21) A probable species in the genus Ranavirus.

Essani K and Granoff A (1989) Intervirology 30, 187

xenotransplantation A shortage of human organs for transplantation therapy has led to studies of other species that might become suitable organ donors for humans. Initially, non-human primates were considered suitable, and more recently pigs. However in each case there has been concern about possible transmission to the recipient of endogenous or exogenous viruses found in the donor species.

Boveva RS et al (2001) Clin Microbiol Revs 14,1

xenotropic murine type C viruses A subspecies of the genus Gammaretrovirus which is endogenous in mice, and infects and replicates efficiently only in cells from a species other than the mouse. The restriction is based on the surface glyco-protein (gp70) of the virus, for which mouse cells do not carry available receptors on their surface. This may be because the receptors are blocked by glycoproteins of the endogenous xenotropic virus. The first xenotropic virus was identified in NZB mice, but all strains may carry such viruses. They all show similar interference tests, p30 and reverse transcriptase. They differ, however, in p12, gp70 and nucleic acid sequences. a or class II viruses are inducible by idoxuridine. May be present in mouse strains which also have an ecotropic virus. ß or class III viruses are not inducible and are produced spontaneously, but only by a few mouse strains and these strains do not produce ecotropic viruses.

Levy JA (1978) Curr Top Microbiol Immun 79, 111

xenotropic virus An endogenous virus which will not replicate complete virus particles in cells of the species in which it occurs naturally. Sometimes called X tropic or S tropic viruses.

Xiburema virus (XIBV) An unassigned vertebrate rhabdovirus, antigenically unrelated to other rhabdoviruses. Isolated from Sabethes (Sbn) intermedias in Brazil in 1977.

Xingu virus (XINV) A strain of Bunyamwera virus in the genus Bunyavirus. Isolated from a human (blood). Not known to cause human disease.

Calisher CH et al (1986) Am J Trop Med Hyg 35, 429

Xiphophorus retrovirus A C-type virus found in melanoma tissue of platyfish, Xiphophorus maculatus. Probably an endogenous virus. The reverse transcrip-tase of the virus was found to cross-react with the Feline leukemia virus reverse transcriptase. The possible role of Xiphophorus retrovirus in tumor formation has not been established.

Petry H et al (1992) Virology 188, 785

Xiwanga virus

Xiwanga virus A possible species in the genus Orbivirus, isolated from phle-botomine sandflies in the Amazon region of Brazil. Antigenically related to Changuinola virus. Not associated with human disease

XJ-cl 3 strain of Junin virus An avirulent strain, non-pathogenic for guinea pigs.

XJ virus A strain of Junin virus in the genus Arenavirus.

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