Effect of the fermented milk on Ig production of human PBL

The Ig production stimulating effect of the fermented milk on Ig production by human PBL was examined under the serum-free condition. Human PBL were inoculated at 1x106 cells/ml in ITES-ERDF medium supplemented with various concentrations of the fermented milk, and cultured for 4 d. The effect on IgM and IgG production was examined. IgM and production by human PBL was facilitated 2.8-fold by the fermented milk at 530 ^g/ml. IgG production was also enhanced 5.4fold (Fig. 1). It is suggested from this fact that the effect is due to not increase in cell number, but facilitation of Ig productivity of PBL by the fermented milk m s s o s

10 1 Protein conc

10 1 Protein conc

Figure 1. Effect of the fermented milk on IgG production of human PBL.

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