Recently, more than seventeen therapeutic Mabs are lunched in U.S., the minimizing the cost of goods is one of the topics for industrialization of Mabs, since productivity directly has impact on effect for the cost. Therefore, various investigations have been made to improve the productivity, for example: changing temperature, adding n-butyric acids,

iron citrate or ethanolamine and so on. We screened substances and find Q10 has some activity enhance for SPR.

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