Antibacterial activity

Most penicillins have a broad spectrum of activity and can be used against both Gram-negative and Gram-positive organisms. Benzylpenicillin and its long-acting formulations (procaine benzylpenicillin and benzathine penicillin) are particularly active against syphilis. Flucloxacillin is active against Staphylococcus aureus, and is often used first-line to treat skin infections. Amoxicillin has a wide range of activity, including action against Haemophilus influenzae and Neisseria gonorrhoee. The newer generations of penicillins on the market have been designed either to work against P-lactamase-resistant organisms or to have antipseudomonal activity.

0 0

Post a comment