The future

Combination therapy within the context of integrated care pathways promises better management of cachexia. At present, clinical trials are hampered by heterogeneity of patients, difficulty with defining end points, mild to moderate activity of combination regimens, loss of patients, and cost. Greater understanding of the complex pathophysiology of both cachexia and anorexia will hopefully provide new targets for drugs, which, in combination with better trial design, should lead to future progress.

0 0

Post a comment