Why is cachexia important

Anorexia and fatigue are consistently among the most common symptoms reported by patients with advanced cancer. Cachexia affects over 80% of such patients or patients with AIDS before death. It is particularly common in those with solid tumours of the upper gastrointestinal tract and lung. Those with cachexia have reduced survival, often experience anorexia and fatigue, have an altered body image, and have impaired physical activity and overall quality of life. Response to antineoplastic therapy is reduced and morbidity caused by treatment increased. Cachexia is usually progressive and is sometimes fatal.

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