The choice of insulin preparation is based on the duration of action. Although insulins can be broadly classified as having very short, short, medium or long duration of action, their effect varies considerably from one patient to another and can be discovered in the individual patient only by trial and error. There are several preparations of medium acting insulins, but those most often used are either one of the isophane preparations or less frequently Human Monotard zinc insulin preparation (see box on page 19).
Most patients (85%) now use insulin of human sequence, a few prefer porcine preparations, while use of some insulin
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