Nursing Management Post Infection Of Ebola Virus

The looming threat of bioterrorism. Science 1999, 283, 1279-1282. 2. Monto, A. The role of antivirals in the control of influenza. Vaccine 2003, 21, 1796-1800. 3. Bray, M Roy, C. J. Antiviral prophylaxis of smallpox. J. Antimicrob. Chemother. 2004,54, 1-5. 5. Eitzen, E. M. Use of biological weapons. In Textbook of Military Medicine, Office of the Surgeon General, Department of the Army, Washington, DC, 1997, pp. 437-450. 6. Eitzen, E. M. Takafuji, E. Historical overview of...

SAH Hydrolase Inhibitors

SAH hydrolase is an intracellular enzyme that regulates biological transmethylation in general. Since many animal viruses require SAH hydrolase in the methylation of the 5'-terminal residue of viral mRNA for forming the cap structure necessary for viral protein translation and replication, this enzyme has been recognized as a suitable antiviral target.112-116 3-Deazaneplanocin A 9 c3-NPC A and carbocyclic 3-deazaadenosine 10 C-c3Ado are two representative inhibitors. Their in vitro activity is...

Preface

When I was just beginning my career at the National Institutes of Health as an organic chemist who wished to contribute to medicine in some way, I was advised to stay away from research on the discovery of antiviral agents since viruses were well under control. That was when the World Health Organization nearly had eliminated variola virus, the causative agent of smallpox and the worst killer in human history. Years earlier, Salk, Sabin, and Koprowski had given the world the means to eliminate...