Example Covariance Pattern Models For Normal Data

The hypertension trial analysed in Sections 1.3 and 2.5 is now considered as repeated measures data. DBP recorded at each of the fortnightly post-treatment visits will be analysed and the effect of centres will be ignored. The primary objective is to obtain an overall estimate of the treatment difference. The number of patients attending at each visit is summarised by treatment below. Visits 3-6 are the four post-treatment visits and visit 2 values are used as the baseline covariate.

Visit

Treatment

Total

A

B

C

1

106

101

104

311

2

106

100

102

308

3

100

96

94

290

4

95

91

94

280

5

87

88

93

268

6

83

84

91

258

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