Robin Prescott

Medical Statistics Unit Public Health Sciences University of Edinburgh UK

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Library of Congress Cataloging-in-Publication Data:

Brown, Helen, 1962-

Applied mixed models in medicine / Helen Brown andRobin Prescott. - 2nd ed.

Includes bibliographical references and index. ISBN-13:978-0-470-02356-3 (cloth: alk. paper) ISBN-10:0-470-02356-2 (cloth: alk. paper)

1. Medicine - Research - Statisticalmethods. 2. Medicine - Statistical methods. 3. Statistics. I. Prescott, Robin. II. Title.

[DNLM: 1. Medicine. 2. Statistics - methods. 3. Models, Statistical. WA950B878a2006] R853.S7B76 2006 610.72' 7 - dc22


British Library Cataloguing in Publication Data

A catalogue record for this book is available from the British Library

ISBN-13: 9 78-0-470-02356-3 (HB) ISBN-10: 0-470-02356-2 (HB)

Typeset in 10/12pt Photina by Laserwords Private Limited, Chennai, India

Printed and bound in Great Britain by TJ International, Padstow, Cornwall

This book is printed on acid-free paper responsibly manufactured from sustainable forestry in which at least two trees are planted for each one used for paper production.

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