Sergio Pedrazzoli, Claudio Pasquali, Cosimo Sperti Introduction
In 1959, Letton and Wilson reported the first non-resective treatment of traumatic rupture of the neck of the pancreas. The right stump of the pancreatic head was oversewn, and a Roux-en-Y loop of jejunum was anastomosed to the left body/tail of the pancreas. In 1984, Dagradi and Serio reported the first central pancreatectomy for an insulinoma, and in 1988, Fagniez, Kracht, and Rotman reported two central pancreatectomies performed for an insulinoma and a serous cystadenoma. At least 150 central pancreatectomies have been reported so far without mortality. Central pancreatectomy involves anatomic removal of benign or borderline lesions of the neck and/or proximal body of the pancreas together with 1 cm of normal tissue on both sides. The goal is to preserve at least 5 cm of the normal pancreatic tissue of the body/tail of the pancreas that would otherwise be removed with a complete left pancreatectomy.
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For centuries, ever since the legendary Ponce de Leon went searching for the elusive Fountain of Youth, people have been looking for ways to slow down the aging process. Medical science has made great strides in keeping people alive longer by preventing and curing disease, and helping people to live healthier lives. Average life expectancy keeps increasing, and most of us can look forward to the chance to live much longer lives than our ancestors.