Indications and Contraindications

Indications Indications for Pancreas Transplantation

■ Type 1 diabetes mellitus

Indications for Simultaneous Pancreas and Kidney Transplantation

■ Diabetic nephropathy

■ End-stage renal disease

Indication for Pancreas Transplantation After Kidney Transplantation

■ Functioning kidney graft

Indication for Pancreas Transplantation Alone (Severe Complications of Diabetes)

■ Instability of glycemia - unstable, "brittle", insulin-dependent diabetes

■ Progressive retinopathy

■ Progressive neuropathy

Contraindications ■ Coexistent cancer (excluding squamous or basal cell carcinoma of skin)

■ Severe infection

■ Psychiatric disease (psychosis)

■ Peripheral arteriopathy with infection

■ Symptomatic coronary artery disease

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