Indications Insulinomas

■ Selected gastrinomas, somatostatinomas

■ Non-functional neuroendocrine neoplasms, usually <2cm, well-circumscribed, no signs of malignancy

Contraindications ■ Glucagonoma (these are usually malignant and require an anatomic resection)

■ Recent acute pancreatitis

■ Uncontrolled coagulopathy/severe thrombocytopenia

■ Co-morbidities dramatically limiting life expectancy

■ Active peptic ulceration (gastrinoma patients)

■ Signs of malignancy - multiple enlarged lymph nodes, liver metastases

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