An epiphrenic diverticulum is a herniation of a pouch of esophageal mucosa through the musculature of the distal thoracic esophagus within 10 cm of the oesophago-gastric junction. The pathological process is thought to be due to the application of pulsion forces to the mucosa above a functionally obstructing region of abnormal esophageal motility.

In 1804 DeGuise accurately described the symptoms associated with a lower esophageal diverticulum, and in 1898 Reitzenstein provided the first radiological images. Manometry and cinefluorography was used by Cross et al. in 1968 to objectively demonstrate an etiological link between motility disturbance in the distal esophagus and diverticula formation.


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