Chronic Disease

Drug-induced liver disease may also present as chronic disease, such as chronic hepatitis, granulomatous hepatitis, steatohepatitis, chronic cholestasis, and cirrhosis. There are also drugs that cause vascular disorders and hepatic tumors (Table 119-5). Again, the clinical features of these

TABLE 119-3. Drug-Induced Acute Hepatitis

Allopurinol Dihydralazine Dantrolene Fluoxetine

Herbal remedies (germander, valerian)

Isoniazid

Ketoconazole

Minocycline

Nefazodone

Paroxetine

Pyrazinamide

Sertraline

Terbinafine

Tienilic acid

TABLE 119-4. Drug-Induced Acute Cholestasis

ACE inhibitors

Amoxicillin—clavulanic acid

Androgens

Azathioprine

Chlorpromazine

Cyclosporin A

Didanosine

Erythromycin

Estrogens

Sulindac

Tamoxifen

Tricyclic antidepressants

ACE = angiotensin-converting enzyme.

drug-induced chronic liver diseases cannot be distinguished from similar types of chronic liver disease from other etiologies.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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