Concomitant Chemoradiotherapy

A second standard of care, which is at least equivalent to surgery, is primary concomitant chemoradiotherapy (CRT). The benchmark is the Intergroup (RTOG 85-01) study first published in 1992 (Herskovic et al, 1992) then with further follow-up in 1999 (Cooper et al, 1999). Five-year survival was 27% in the CRT group and 0% in the radiation alone group. This study established chemoradiotherapy as a curative option, provided an approach for patients who could not or did not want to have surgery, and confirmed that radiation alone was not curative.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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