Introduction

The feasibility of LDLT is based on the liver's ability to regenerate after surgical resection, and the more detailed knowledge of the segmental anatomy of the liver.

LDLT was first applied in the late 1980s to the pediatric population. Because of a significant size mismatch between pediatric recipients and the (largely adult) deceased donor pool, the mortality of pediatric patients on the waiting list varied from 10 to 50%. The availability of an elective liver transplantation from a living donor source has allowed many programs to decrease their waiting list mortality rate to almost 0%. Adult to adult LDLT (ALDLT) was initially developed in Asia, in countries with no access to a deceased donor source. The initial attempts using the left hepatic lobe in the United States were disappointing. The liver volume obtained with the left lobe was not sufficient for larger size recipients in the Western world. The technique evolved towards the right hepatic lobe, which provided larger liver volumes (60% of total liver volume). The first ALDLT using the right hepatic lobe in the United States was performed in 1997. Currently, LDLT represents approximately 10% of the total liver transplantations performed in adults in the United States. As of January 31, 2003, 1,158 ALDLT had been performed in the United States. Most of these transplantations in adults involved right hepatic lobe donation.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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