Jimmy KoMD and Lloyd MayerMD

The practicing gastroenterologist is frequently confronted with immune-related diseases, such as Crohn's disease (CD), ulcerative colitis (UC), celiac sprue, and pernicious anemia (PA). However, the role of the gastrointestinal (GI) tract as the body's largest lymphoid organ is often overlooked. In fact, the surface area of the GI tract could cover two tennis courts, and within that surface is a rich supply of B- and T-lymphocytes, macrophages, and dendritic cells. The number of lymphocytes in the GI tract exceeds that in the spleen, but unlike other lymphoid organs, immune-associated cells in the GI tract are constantly confronted with antigen (mainly in the form of bacteria and food). Gut-associated lymphoid tissue, generally known as mucosa-associated lymphoid tissue (MALT), regulates immune responses in the gut to maintain homeostasis. Without this tight regulation, inflammation would predominate in the GI tract. Therefore, it is not difficult to imagine how disease can result in the GI tract when immune regulation is disrupted.

Living Gluten Free

Living Gluten Free

A beginners guide that will reveal how living "G" free can help you lose weight today! This is not a fad diet, or short term weight loss program that sometimes makes you worse off than before you started. This is a necessity for some people and is prescribed to 1 out of every 100 people on earth by doctors and health professionals.

Get My Free Ebook


Post a comment