Although laser thermocoagulation was one of the earliest modalities used to treat bleeding peptic ulcers, today it is seldom used due to its expense and technical complexity. A randomized study compared the efficacy of Nd:YAG laser, HP, and MPEC in the treatment of active bleeding from peptic ulcers (Hui et al, 1991). Ninety-one patients were randomized to receive laser, HP, or MPEC. There was no significant difference between the groups in the rate of recurrent bleeding, the duration of hospital stay, and the proportion requiring emergency surgery. However, the cost per patient was higher with laser compared to HP and MPEC.
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